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Query: PCNT

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PCNT 1 2.240 0.094 0.158

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PCNT Phosphorylation S2192 1.692 _SECQDMSLSS(ph)PTSVLGGSR_
PCNT Phosphorylation S1653 1.274 _RES(ph)EVLDLKEQLEK_
PCNT Phosphorylation S2214 0.162 _KS(ph)PVGMLDLSSWSSPEVLR_
PCNT Phosphorylation S2177 0.088 _NWDSLIPDEMPDS(ph)PIQEK_
PCNT Phosphorylation S2327 0.058 _DVEDFITTSFDSQETLSS(ph)PPPGLEGK_
PCNT Ubiquitylation K3099 -0.180 _SAWK(gl)PDETAPQSSLR_
PCNT Phosphorylation S2352 -0.599 -0.395 _LS(ph)PGSGGPEAQTAGPVTPASISGR_
PCNT Phosphorylation S2355 -0.685 -0.511 _LSPGS(ph)GGPEAQTAGPVTPASISGR_
PCNT Ubiquitylation K505 1.075 _VEDLEQLK(gl)QR_
PCNT Ubiquitylation K2685 -0.556 _ESQSAK(gl)ALEELR_

Background Information for PCNT:


Pubmed-PCNT »
Uniprot-PCNT »
Biogrid-PCNT »
ProteomicsDB-PCNT »

Tumorportal-PCNT »
COSMIC-PCNT »
GenomeRNAi-PCNT »
Genecards-PCNT


Protein-protein Interactions for PCNT
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDK5RAP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP120 Cat. description Hein, Mann, Cell 2015
Category members IP bait FGFR1OP Cat. description Hein, Mann, Cell 2015
Category members IP bait MAPRE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PAX6 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCNT Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKACB Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKAR2A Cat. description Hein, Mann, Cell 2015
Category members IP bait RACGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TAPT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait YWHAZ Cat. description Hein, Mann, Cell 2015
Category members IP bait BIRC7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1orf87 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EXOC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM81B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IKBIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1984 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPXN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MIS18A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MZT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCP10L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSNAX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TXNDC11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PCNT
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PACT_domain IPR019528 0


Protein complexes (CORUM database) featuring PCNT
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3714 Pericentrin-GCP complex Database 0


Categories featuring PCNT
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0005516 calmodulin binding Database 0.74
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0000226 microtubule cytoskeleton organization Database 0.5
Category members Pathway Pathway_727 REACTOME_MITOTIC_G2_G2_M_PHASES 0 0.46
Category members Pathway Pathway_728 REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES 0 0.4
Category members GO Category GO:0005815 microtubule organizing center Database 0.39
Category members Pathway Pathway_730 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES 0 0.33
Category members GO Category GO:0000086 G2/M transition of mitotic cell cycle Database 0.33
Category members GO Category GO:0045171 intercellular bridge Database 0.32
Category members Disease phenotype Seckel_syndrome Seckel syndrome Database 0.25
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0021772 olfactory bulb development Database 0.06
Category members GO Category GO:0007051 spindle organization Database 0.04
Category members GO Category GO:0035264 multicellular organism growth Database 0.04
Category members Pathway Pathway_1153 BIOCARTA_AKAPCENTROSOME_PATHWAY 0 0
Category members GO Category GO:0001764 neuron migration Database 0
Category members GO Category GO:0005814 centriole Database 0
Category members GO Category GO:0021696 cerebellar cortex morphogenesis Database 0
Category members GO Category GO:0035108 limb morphogenesis Database 0
Category members GO Category GO:0042384 cilium assembly Database 0
Category members GO Category GO:0048854 brain morphogenesis Database 0
Category members GO Category GO:0061351 neural precursor cell proliferation Database 0


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