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Query: PACSIN3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PACSIN3 1 5.811 0.140 0.230 1.239 0.925

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PACSIN3 Phosphorylation S320 0.462 0.580 _GGRS(ph)PDEVTLTSIVPTR_
PACSIN3 Phosphorylation S355 -0.685 -0.861 _DGTAPPPQSPGSPGTGQDEEWS(ph)DEESPR_
PACSIN3 Ubiquitylation K148 1.059 _LK(gl)EVEASKK_
PACSIN3 Ubiquitylation K154 0.880 _LKEVEASK(gl)K_
PACSIN3 Phosphorylation T348 1.778 _DGTAPPPQSPGSPGT(ph)GQDEEWSDEESPRK_

Background Information for PACSIN3:


Pubmed-PACSIN3 »
Uniprot-PACSIN3 »
Biogrid-PACSIN3 »
ProteomicsDB-PACSIN3 »

Tumorportal-PACSIN3 »
COSMIC-PACSIN3 »
GenomeRNAi-PACSIN3 »
Genecards-PACSIN3


Protein-protein Interactions for PACSIN3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANLN Cat. description Hein, Mann, Cell 2015
Category members IP bait ATP6AP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP4B Cat. description Hein, Mann, Cell 2015
Category members IP bait COBLL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DCTN3 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNB Cat. description Hein, Mann, Cell 2015
Category members IP bait FLOT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GJB2 Cat. description Hein, Mann, Cell 2015
Category members IP bait HAUS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH10 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait PDGFRA Cat. description Hein, Mann, Cell 2015
Category members IP bait POLH Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait PTPN23 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait TMOD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait PACSIN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PACSIN3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PACSIN3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SH3_2 IPR011511 0.08
Category members FCH_dom IPR001060 0
Category members SH3_domain IPR001452 0


Protein complexes (CORUM database) featuring PACSIN3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PACSIN3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0008092 cytoskeletal protein binding Database 0.5
Category members GO Category GO:0006897 endocytosis Database 0.31
Category members GO Category GO:0008289 lipid binding Database 0
Category members GO Category GO:0019855 calcium channel inhibitor activity Database 0
Category members GO Category GO:0045806 negative regulation of endocytosis Database 0
Category members GO Category GO:0051044 positive regulation of membrane protein ectodomain proteolysis Database 0
Category members GO Category GO:0051926 negative regulation of calcium ion transport Database 0


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