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Query: NSMCE1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NSMCE1 0 -2.899 0.000 -0.240 -2.531 0.668

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NSMCE1 Ubiquitylation K143 -1.036 _K(gl)KEAEQVLQK_
NSMCE1 Ubiquitylation K144 -1.036 _K(gl)KEAEQVLQK_

Background Information for NSMCE1:





Protein-protein Interactions for NSMCE1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SMC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait EID3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAGEB10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NSMCE1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OBFC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF597 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NSMCE1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PE/DAG-bd IPR002219 0.63
Category members Znf_RING IPR001841 0


Protein complexes (CORUM database) featuring NSMCE1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NSMCE1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0006310 DNA recombination Database 3.14
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0000781 chromosome, telomeric region Database 0.16
Category members GO Category GO:0030915 Smc5-Smc6 complex Database 0.15
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0035556 intracellular signal transduction Database 0


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