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Query: NRBP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NRBP1 0 2.631 -1.270 2.090

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NRBP1 Phosphorylation S2 0.201 0.232 _S(ph)EGESQTVLSSGSDPK_
NRBP1 Phosphorylation S11 0.309 -0.085 _(ac)SEGESQTVLS(ph)SGSDPK_
NRBP1 Phosphorylation T441 -0.603 -0.439 _TPT(ph)PEPAEVETR_

Background Information for NRBP1:


Pubmed-NRBP1 »
Uniprot-NRBP1 »
Biogrid-NRBP1 »
ProteomicsDB-NRBP1 »

Tumorportal-NRBP1 »
COSMIC-NRBP1 »
GenomeRNAi-NRBP1 »
Genecards-NRBP1


Protein-protein Interactions for NRBP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BPGM Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CA10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DNA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM117B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSC22D3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSC22D4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NRBP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring NRBP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NRBP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005938 cell cortex Database 2.26
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0006888 ER to Golgi vesicle-mediated transport Database 0.28
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0006367 transcription initiation from RNA polymerase II promoter Database 0.25
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members Pathway Pathway_822 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY 0 0.09
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_929 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY 0 0
Category members GO Category GO:0012505 endomembrane system Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0


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