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Query: NNT

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NNT 1 4.184 -1.550 3.290 0.491 0.403

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for NNT:


Pubmed-NNT »
Uniprot-NNT »
Biogrid-NNT »
ProteomicsDB-NNT »

Tumorportal-NNT »
COSMIC-NNT »
GenomeRNAi-NNT »
Genecards-NNT


Protein-protein Interactions for NNT
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC26 Cat. description Hein, Mann, Cell 2015
Category members IP bait HUWE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait JUNB Cat. description Hein, Mann, Cell 2015
Category members IP bait MIS12 Cat. description Hein, Mann, Cell 2015
Category members IP bait MKLN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NEIL3 Cat. description Hein, Mann, Cell 2015
Category members IP bait PAPD5 Cat. description Hein, Mann, Cell 2015
Category members IP bait PAPSS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SLAIN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait WIZ Cat. description Hein, Mann, Cell 2015
Category members IP bait CD97 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPRC5C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDUFS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SUSD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NNT
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members AlaDH/PNT_NAD(H)-bd IPR007698 0
Category members AlaDH/PNT_N IPR007886 0
Category members DHS-like_NAD/FAD-binding_dom IPR029035 0


Protein complexes (CORUM database) featuring NNT
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NNT
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0006099 tricarboxylic acid cycle Database 2.74
Category members Pathway Pathway_12 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE 0 1.87
Category members Pathway Pathway_10 REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE 0 1.76
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0051287 NAD binding Database 1.6
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0005746 mitochondrial respiratory chain Database 0.18
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0044237 cellular metabolic process Database 0.08
Category members Pathway Pathway_13 REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT 0 0.04
Category members Disease phenotype Familial_glucocorticoid_deficiency Familial glucocorticoid deficiency Database 0.04
Category members GO Category GO:0015992 proton transport Database 0.04
Category members Pathway Pathway_281 KEGG_NICOTINATE_AND_NICOTINAMIDE_METABOLISM 0 0
Category members GO Category GO:0008746 NAD(P)+ transhydrogenase activity Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0050661 NADP binding Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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