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Query: NFYC

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NFYC 0 1.610 -1.080 1.710 -0.084 0.484

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NFYC Ubiquitylation K36 -0.455 -0.045 _NLTVK(gl)DFR_

Background Information for NFYC:


Pubmed-NFYC »
Uniprot-NFYC »
Biogrid-NFYC »
ProteomicsDB-NFYC »

Tumorportal-NFYC »
COSMIC-NFYC »
GenomeRNAi-NFYC »
Genecards-NFYC


Protein-protein Interactions for NFYC
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait NFYA Cat. description Hein, Mann, Cell 2015
Category members IP bait NFYB Cat. description Hein, Mann, Cell 2015
Category members IP bait NFYC Cat. description Hein, Mann, Cell 2015
Category members IP bait COMMD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NFYA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRR20E Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NFYC
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Histone_core_D IPR007125 0.12
Category members Histone-fold IPR009072 0.01
Category members CBFA_NFYB_domain IPR003958 0


Protein complexes (CORUM database) featuring NFYC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 4478 CBF-DNA complex Database 0.04
Category members Corum 4498 p32-CBF-DNA complex Database 0


Categories featuring NFYC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0006457 protein folding Database 4.93
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members Pathway Pathway_383 PID_P53_DOWNSTREAM_PATHWAY 0 0.23
Category members Pathway Pathway_142 PID_MYC_REPRESS_PATHWAY 0 0.21
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members Pathway Pathway_767 KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION 0 0.09
Category members GO Category GO:0016602 CCAAT-binding factor complex Database 0.04
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0044255 cellular lipid metabolic process Database 0


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