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Query: NFIC

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NFIC 0 2.677 -0.620 0.210
NFIC 0 2.677 -0.620 0.210 -0.711 0.025 0.306 1.031

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NFIC Phosphorylation S325 0.852 _KPEKPLFS(ph)SASPQDSSPR_
NFIC Phosphorylation T314 0.827 _DQDMSSPT(ph)TMK_
NFIC Phosphorylation S312 0.764 0.746 _DQDMSS(ph)PTTMK_
NFIC Phosphorylation S311 1.021 0.671 _DQDMS(ph)SPTTM(ox)K_
NFIC Phosphorylation S328 1.295 0.637 _KPEKPLFSSAS(ph)PQDSSPR_
NFIC Phosphorylation S323 0.317 0.328 _NWTEDM(ox)EGGISS(ph)PVKK_
NFIC Phosphorylation S322 0.191 0.020 _NWTEDMEGGIS(ph)SPVKK_
NFIC Phosphorylation S304 -0.547 -0.146 _SGSMEEDVDTSPGGDYYTSPS(ph)SPTSSSR_
NFIC Phosphorylation S294 -0.140 -0.153 _SGSMEEDVDTS(ph)PGGDYYTSPS(ph)SPTSSSR_
NFIC Phosphorylation S305 -0.748 -0.199 _SGSMEEDVDTSPGGDY(ph)YTSPSS(ph)PTSSSR_
NFIC Phosphorylation S333 0.309 -0.312 _TEMDKS(ph)PFNSPSPQDSPR_
NFIC Phosphorylation S332 -0.428 -1.102 _KPEKPLFSSASPQDS(ph)SPR_
NFIC Phosphorylation S339 -1.705 -1.357 _SPFNSPS(ph)PQDSPR_
NFIC Phosphorylation S294 -1.873 _TISIDENM(ox)EPSPTGDFYPSPS(ph)SPAAGSR_
NFIC Phosphorylation S295 -1.280 _TISIDENMEPSPTGDFYPSPSS(ph)PAAGSR_
NFIC Phosphorylation S300 -1.728 _TISIDENM(ox)EPSPTGDFYPSPSSPAAGS(ph)R_
NFIC Phosphorylation S333 -0.428 _KPEKPLFSSASPQDS(ph)SPR_

Background Information for NFIC:


Pubmed-NFIC »
Uniprot-NFIC »
Biogrid-NFIC »
ProteomicsDB-NFIC »

Tumorportal-NFIC »
COSMIC-NFIC »
GenomeRNAi-NFIC »
Genecards-NFIC


Protein-protein Interactions for NFIC
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CTR9 Cat. description Hein, Mann, Cell 2015
Category members IP bait NCBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NFIB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TH Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NFIC
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members CTF/NFI IPR000647 0
Category members MAD_homology1_Dwarfin-type IPR003619 0
Category members MAD_homology_MH1 IPR013019 0
Category members CTF/NFI_DNA-bd_N IPR019548 0
Category members CTF/NFI_DNA-bd-dom IPR020604 0


Protein complexes (CORUM database) featuring NFIC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NFIC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006260 DNA replication Database 3.34
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0003690 double-stranded DNA binding Database 0.66
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0007179 transforming growth factor beta receptor signaling pathway Database 0.25
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0001159 core promoter proximal region DNA binding Database 0.04
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members Pathway Pathway_186 PID_HNF3A_PATHWAY 0 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0042475 odontogenesis of dentin-containing tooth Database 0


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