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Query: NDNL2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NDNL2 1 -0.798 -1.630 2.620 -1.210 -0.392

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NDNL2 Ubiquitylation K260 -0.249 _TNLETSK(gl)MK_
NDNL2 Ubiquitylation K262 -0.249 _TNLETSK(gl)MK_
NDNL2 Phosphorylation S60 -0.694 _GPGGSQGS(ph)QGPSPQGAR_
NDNL2 Phosphorylation S64 -1.141 -1.086 _GPGGSQGSQGPS(ph)PQGAR_
NDNL2 Ubiquitylation K83 0.267 _SQK(gl)QLELK_

Background Information for NDNL2:





Protein-protein Interactions for NDNL2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SMC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait EID3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NSMCE1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NSMCE4A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OBFC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PJA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF597 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NDNL2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members MAGE IPR002190 0


Protein complexes (CORUM database) featuring NDNL2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NDNL2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006310 DNA recombination Database 3.14
Category members GO Category GO:0000781 chromosome, telomeric region Database 0.16
Category members GO Category GO:0030915 Smc5-Smc6 complex Database 0.15
Category members Pathway Pathway_557 PID_P75_NTR_PATHWAY 0 0.04
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0031398 positive regulation of protein ubiquitination Database 0
Category members GO Category GO:0040008 regulation of growth Database 0


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