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Query: MUS81

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MUS81 0 -0.660

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MUS81 Phosphorylation S95 -0.268 -0.392 _TSGGDHAPDS(ph)PSGENSPAPQGR_

Background Information for MUS81:


Pubmed-MUS81 »
Uniprot-MUS81 »
Biogrid-MUS81 »
ProteomicsDB-MUS81 »

Tumorportal-MUS81 »
COSMIC-MUS81 »
GenomeRNAi-MUS81 »
Genecards-MUS81


Protein-protein Interactions for MUS81
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CEP170 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait MUS81 Cat. description Hein, Mann, Cell 2015
Category members IP bait NPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait SORT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP72 Cat. description Hein, Mann, Cell 2015


Protein Domains in MUS81
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ERCC4_domain IPR006166 0
Category members DNA_pol_b-like_N IPR010996 0
Category members Restrct_endonuc-II-like IPR011335 0


Protein complexes (CORUM database) featuring MUS81
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 13 MUS81-CDS1 complex Database 0.24


Categories featuring MUS81
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0006310 DNA recombination Database 3.14
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_343 KEGG_HOMOLOGOUS_RECOMBINATION 0 0.12
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0004518 nuclease activity Database 0.09
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0048257 3'-flap endonuclease activity Database 0


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