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Query: MTX2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MTX2 0 0.461 -0.150 0.000
MTX2 0 0.461 -0.150 0.000 -0.266 0.630 0.503

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MTX2 Ubiquitylation K177 -0.406 _AIGWGKK(gl)_

Background Information for MTX2:


Pubmed-MTX2 »
Uniprot-MTX2 »
Biogrid-MTX2 »
ProteomicsDB-MTX2 »

Tumorportal-MTX2 »
COSMIC-MTX2 »
GenomeRNAi-MTX2 »
Genecards-MTX2


Protein-protein Interactions for MTX2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MTX2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CD244 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MTX2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Glutathione-S-Trfase_C-like IPR010987 0.23
Category members Thioredoxin-like_fold IPR012336 0.16
Category members Sam37/metaxin IPR019564 0


Protein complexes (CORUM database) featuring MTX2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MTX2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005741 mitochondrial outer membrane Database 0.46
Category members Pathway Pathway_9 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT 0 0.33
Category members GO Category GO:0006626 protein targeting to mitochondrion Database 0.11
Category members GO Category GO:0006839 mitochondrial transport Database 0


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