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Query: MTX1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MTX1 0 0.378 -0.307 0.032

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MTX1 Ubiquitylation K227 0.228 0.424 _EK(gl)YNADYDLSAR_

Background Information for MTX1:


Pubmed-MTX1 »
Uniprot-MTX1 »
Biogrid-MTX1 »
ProteomicsDB-MTX1 »

Tumorportal-MTX1 »
COSMIC-MTX1 »
GenomeRNAi-MTX1 »
Genecards-MTX1


Protein-protein Interactions for MTX1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MTX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait APLNR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1orf85 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CACNG4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EDNRA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GNRH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR2C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KCNIP4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPAR4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SIGLEC12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC15A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC2A12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC39A12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC39A9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM108 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM171 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VIPR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MTX1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Glutathione-S-Trfase_C-like IPR010987 0.23
Category members Metaxin IPR017410 0
Category members Sam37/metaxin IPR019564 0


Protein complexes (CORUM database) featuring MTX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MTX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005741 mitochondrial outer membrane Database 0.46
Category members Pathway Pathway_9 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT 0 0.33
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0006626 protein targeting to mitochondrion Database 0.11


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