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Query: MTMR2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MTMR2 1 3.693 -1.600 3.150

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MTMR2 Phosphorylation S58 0.107 0.436 _SASVVSSDSISTSADNFS(ph)PDLR_

Background Information for MTMR2:


Pubmed-MTMR2 »
Uniprot-MTMR2 »
Biogrid-MTMR2 »
ProteomicsDB-MTMR2 »

Tumorportal-MTMR2 »
COSMIC-MTMR2 »
GenomeRNAi-MTMR2 »
Genecards-MTMR2


Protein-protein Interactions for MTMR2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MTMR2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MTMR2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members GRAM IPR004182 0.18
Category members Tyr/Dual-sp_Pase IPR000387 0
Category members Tyr_Pase_cat IPR003595 0
Category members Myotubularin-like_Pase_dom IPR010569 0
Category members Prot-tyrosine_phosphatase-like IPR029021 0


Protein complexes (CORUM database) featuring MTMR2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MTMR2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0043197 dendritic spine Database 0.86
Category members GO Category GO:0051262 protein tetramerization Database 0.6
Category members GO Category GO:0031901 early endosome membrane Database 0.58
Category members GO Category GO:0046855 inositol phosphate dephosphorylation Database 0.58
Category members GO Category GO:0046856 phosphatidylinositol dephosphorylation Database 0.35
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0008021 synaptic vesicle Database 0.28
Category members GO Category GO:0030425 dendrite Database 0.26
Category members GO Category GO:0030424 axon Database 0.23
Category members Pathway Pathway_58 KEGG_FRUCTOSE_AND_MANNOSE_METABOLISM 0 0.1
Category members GO Category GO:0006661 phosphatidylinositol biosynthetic process Database 0.06
Category members Pathway Pathway_103 REACTOME_PI_METABOLISM 0 0.04
Category members GO Category GO:0031642 negative regulation of myelination Database 0.03
Category members GO Category GO:0032288 myelin assembly Database 0.02
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_101 KEGG_RIBOFLAVIN_METABOLISM 0 0
Category members Pathway Pathway_104 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE 0 0
Category members Pathway Pathway_105 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members GO Category GO:0002091 negative regulation of receptor internalization Database 0
Category members GO Category GO:0004725 protein tyrosine phosphatase activity Database 0
Category members GO Category GO:0005774 vacuolar membrane Database 0
Category members GO Category GO:0006470 protein dephosphorylation Database 0
Category members GO Category GO:0006644 phospholipid metabolic process Database 0
Category members GO Category GO:0008138 protein tyrosine/serine/threonine phosphatase activity Database 0
Category members GO Category GO:0014069 postsynaptic density Database 0
Category members GO Category GO:0016311 dephosphorylation Database 0
Category members GO Category GO:0016791 phosphatase activity Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0045806 negative regulation of endocytosis Database 0
Category members GO Category GO:0046488 phosphatidylinositol metabolic process Database 0
Category members GO Category GO:0048666 neuron development Database 0


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