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Query: MTA3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MTA3 0 3.330 -0.430 1.040
MTA3 0 3.330 -0.430 1.040 0.282 0.258 0.926 0.072 0.430

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MTA3 Phosphorylation S428 0.030 _MPTQSEEEKLS(ph)PSPTTEDPR_
MTA3 Ubiquitylation K509 -0.005 -0.041 _AECK(gl)MLLNS_
MTA3 Phosphorylation S519 0.339 -0.158 _HAELSGS(ph)PLK_
MTA3 Ubiquitylation K32 -0.505 _RIEELNK(gl)TASGNVEAK_

Background Information for MTA3:


Pubmed-MTA3 »
Uniprot-MTA3 »
Biogrid-MTA3 »
ProteomicsDB-MTA3 »

Tumorportal-MTA3 »
COSMIC-MTA3 »
GenomeRNAi-MTA3 »
Genecards-MTA3


Protein-protein Interactions for MTA3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDK2AP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HDAC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait KPNA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MBD2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MTA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MTA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TCF20 Cat. description Hein, Mann, Cell 2015
Category members IP bait ZMYND8 Cat. description Hein, Mann, Cell 2015
Category members IP bait C9orf25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CGB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GATAD2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GATAD2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HDAC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IKZF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MBD3L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PHF20L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBBP7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCF19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF219 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF800 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MTA3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SANT/Myb IPR001005 2.18
Category members BAH_dom IPR001025 0.62
Category members ELM2_dom IPR000949 0.51
Category members Znf_GATA IPR000679 0.29
Category members Homeodomain-like IPR009057 0


Protein complexes (CORUM database) featuring MTA3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 41 Mi-2/NuRD-MTA2 complex Database 0.67
Category members Corum 585 Mi2/NuRD-BCL6-MTA3 complex Database 0.67


Categories featuring MTA3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0016581 NuRD complex Database 1.15
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0008278 cohesin complex Database 0.44
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members Pathway Pathway_54 BIOCARTA_MTA3_PATHWAY 0 0.36
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0010971 positive regulation of G2/M transition of mitotic cell cycle Database 0.07
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0


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