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Query: MPP5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MPP5 0 1.370 -0.550 1.720 0.158 0.229 -0.737

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for MPP5:


Pubmed-MPP5 »
Uniprot-MPP5 »
Biogrid-MPP5 »
ProteomicsDB-MPP5 »

Tumorportal-MPP5 »
COSMIC-MPP5 »
GenomeRNAi-MPP5 »
Genecards-MPP5


Protein-protein Interactions for MPP5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait LIN7C Cat. description Hein, Mann, Cell 2015
Category members IP bait YAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ALOX5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HOMER3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MPP5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHAC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF19B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MPP5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members L27 IPR004172 1.84
Category members GK/Ca_channel_bsu IPR008145 1.36
Category members Guanylate_kin-like IPR008144 1.32
Category members L27_C IPR014775 0.33
Category members PDZ IPR001478 0.15
Category members SH3_2 IPR011511 0.08
Category members SH3_domain IPR001452 0


Protein complexes (CORUM database) featuring MPP5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 848 RICH1/AMOT polarity complex, Flag-Amot precipitated Database 0.35
Category members Corum 460 CRB1-MPP5-INADL complex Database 0.11
Category members Corum 461 MPP4-MPP5-CRB1 complex Database 0
Category members Corum 846 RICH1/AMOT polarity complex, Flag-Rich1 precipitated Database 0
Category members Corum 918 PAR3-PAR6-PALS1 complex Database 0


Categories featuring MPP5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0043234 protein complex Database 2.73
Category members Pathway Pathway_413 KEGG_TIGHT_JUNCTION 0 2.08
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005923 tight junction Database 0.69
Category members GO Category GO:0032287 peripheral nervous system myelin maintenance Database 0.62
Category members GO Category GO:0070830 tight junction assembly Database 0.36
Category members GO Category GO:0034329 cell junction assembly Database 0.29
Category members Pathway Pathway_560 REACTOME_CELL_CELL_COMMUNICATION 0 0.25
Category members GO Category GO:0043220 Schmidt-Lanterman incisure Database 0.21
Category members GO Category GO:0035749 myelin sheath adaxonal region Database 0.11
Category members GO Category GO:0045216 cell-cell junction organization Database 0.1
Category members GO Category GO:0032288 myelin assembly Database 0.02
Category members Pathway Pathway_1236 REACTOME_TIGHT_JUNCTION_INTERACTIONS 0 0
Category members Pathway Pathway_1237 REACTOME_CELL_CELL_JUNCTION_ORGANIZATION 0 0
Category members Pathway Pathway_925 REACTOME_CELL_JUNCTION_ORGANIZATION 0 0
Category members GO Category GO:0012505 endomembrane system Database 0
Category members GO Category GO:0043219 lateral loop Database 0


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