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Query: MPHOSPH8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MPHOSPH8 1 5.308 0.330 -0.220 0.872 1.388 0.373

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MPHOSPH8 Phosphorylation S85 1.839 _GYTS(ph)DDDTWEPEIHLEDCK_
MPHOSPH8 Phosphorylation S403 0.718 _GLWSTDS(ph)AEEDKETK_
MPHOSPH8 Phosphorylation S51 0.647 0.507 _GAEAFGDS(ph)EEDGEDVFEVEK_
MPHOSPH8 Phosphorylation S319 0.466 _AGQDMGLEHGFEKPLDSAMS(ph)AEEDTDVR_
MPHOSPH8 Ubiquitylation K623 0.189 _LLITK(gl)GAK_

Background Information for MPHOSPH8:


Pubmed-MPHOSPH8 »
Uniprot-MPHOSPH8 »
Biogrid-MPHOSPH8 »
ProteomicsDB-MPHOSPH8 »

Tumorportal-MPHOSPH8 »
COSMIC-MPHOSPH8 »
GenomeRNAi-MPHOSPH8 »
Genecards-MPHOSPH8


Protein-protein Interactions for MPHOSPH8
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MATR3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MPHOSPH8 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait YIPF5 Cat. description Hein, Mann, Cell 2015
Category members IP bait ESAM Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF597 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MPHOSPH8
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Chromo_domain/shadow IPR000953 2.84
Category members Chromodomain-like IPR016197 2.29
Category members Chromo_domain IPR023780 1.98
Category members Ankyrin_rpt IPR002110 0
Category members Ankyrin_rpt-contain_dom IPR020683 0


Protein complexes (CORUM database) featuring MPHOSPH8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 639 RANBPM-Muskelin-TWA1-HSMpp8 complex Database 0.04


Categories featuring MPHOSPH8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005720 nuclear heterochromatin Database 1.41
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0035064 methylated histone residue binding Database 0.53
Category members GO Category GO:0044030 regulation of DNA methylation Database 0.05
Category members GO Category GO:0000788 nuclear nucleosome Database 0


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