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Query: MLX

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MLX 1 0.314 2.920 -1.160

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MLX Ubiquitylation K173 -1.900 0.566 _LSK(gl)AIVLQK_
MLX Ubiquitylation K209 0.448 _DVTALK(gl)IMK_
MLX Phosphorylation S7 0.036 -0.288 _(ac)TEPGAS(ph)PEDPWVK_

Background Information for MLX:


Pubmed-MLX »
Uniprot-MLX »
Biogrid-MLX »
ProteomicsDB-MLX »

Tumorportal-MLX »
COSMIC-MLX »
GenomeRNAi-MLX »
Genecards-MLX


Protein-protein Interactions for MLX
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MLX Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MLX
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members bHLH_dom IPR011598 0.32


Protein complexes (CORUM database) featuring MLX
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MLX
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006913 nucleocytoplasmic transport Database 2.96
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_5 REACTOME_INTEGRATION_OF_ENERGY_METABOLISM 0 0.9
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members Pathway Pathway_123 BIOCARTA_CHREBP2_PATHWAY 0 0.61
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0006112 energy reserve metabolic process Database 0.21
Category members GO Category GO:0031325 positive regulation of cellular metabolic process Database 0.04
Category members Disease phenotype Takayasu_arteritis Takayasu arteritis Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0046983 protein dimerization activity Database 0


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