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Query: METAP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
METAP1 0 -0.146 0.150 -0.280 0.170 -0.316

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for METAP1:


Pubmed-METAP1 »
Uniprot-METAP1 »
Biogrid-METAP1 »
ProteomicsDB-METAP1 »

Tumorportal-METAP1 »
COSMIC-METAP1 »
GenomeRNAi-METAP1 »
Genecards-METAP1


Protein-protein Interactions for METAP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait CBWD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CBWD2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPPR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NAA40 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPPA Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in METAP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Pept_M24_MAP IPR001714 0.04
Category members Pept_M24_structural-domain IPR000994 0
Category members Pept_M24A_MAP1 IPR002467 0


Protein complexes (CORUM database) featuring METAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring METAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0008235 metalloexopeptidase activity Database 0.33
Category members GO Category GO:0018206 peptidyl-methionine modification Database 0.3
Category members GO Category GO:0007603 phototransduction, visible light Database 0.25
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members GO Category GO:0004177 aminopeptidase activity Database 0.13
Category members GO Category GO:0031365 N-terminal protein amino acid modification Database 0.13
Category members GO Category GO:0016056 rhodopsin mediated signaling pathway Database 0.04
Category members GO Category GO:0022400 regulation of rhodopsin mediated signaling pathway Database 0
Category members GO Category GO:0006417 regulation of translation Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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