bioLOGIC-db

bioLOGIC Data

Query: MED27

[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
MED27	0	-0.399	-0.870	1.300	-3.189

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
MED27	Ubiquitylation	K275	1.039	0.452	_SYIK(gl)LFQAPCQR_
MED27	Ubiquitylation	K145		-0.804	_SANQMGVSAK(gl)R_

ProteomicsDB-MED27 »

Protein-protein Interactions for MED27

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait CDK8	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait MED12	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait MED22	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait CCNC	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CDK19	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CDK8	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait MED1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait MED18	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait MED19	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait MED21	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait MED7	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in MED27

	Domain name	Domain Description	TC-NER relevance -log10(p-value)

Protein complexes (CORUM database) featuring MED27

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	Corum	230	Mediator complex	Database	0.76
Category members	Corum	535	TRAP complex	Database	0.76
Category members	Corum	300	PC2 complex	Database	0.53
Category members	Corum	5450	Mediator complex	Database	0.45
Category members	Corum	301	SMCC complex	Database	0.45
Category members	Corum	547	SMCC complex	Database	0.31
Category members	Corum	217	CRSP complex	Database	0
Category members	Corum	218	CRSP complex	Database	0

Categories featuring MED27

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005634	nucleus	Database	INF
Category members	GO Category	GO:0005654	nucleoplasm	Database	INF
Category members	GO Category	GO:0010467	gene expression	Database	INF
Category members	GO Category	GO:0005730	nucleolus	Database	13.38
Category members	GO Category	GO:0005737	cytoplasm	Database	12.81
Category members	GO Category	GO:0003713	transcription coactivator activity	Database	3.68
Category members	Pathway	Pathway_90	REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION	0	0.88
Category members	GO Category	GO:0016592	mediator complex	Database	0.53
Category members	GO Category	GO:0019827	stem cell maintenance	Database	0.48
Category members	Pathway	Pathway_41	REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION	0	0.35
Category members	Pathway	Pathway_42	REACTOME_DEVELOPMENTAL_BIOLOGY	0	0.32
Category members	GO Category	GO:0006367	transcription initiation from RNA polymerase II promoter	Database	0.25
Category members	Pathway	Pathway_1	REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM	0	0.23
Category members	GO Category	GO:0005667	transcription factor complex	Database	0.19
Category members	GO Category	GO:0006357	regulation of transcription from RNA polymerase II promoter	Database	0.19
Category members	Pathway	Pathway_822	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	0	0.09
Category members	Pathway	Pathway_4	REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS	0	0