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Query: MED20

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MED20 1 -1.071 2.740 -1.100 -0.895

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MED20 Ubiquitylation K106 -0.176 _GFFQSAK(gl)ASK_
MED20 Ubiquitylation K202 -0.568 _K(gl)QQQVPVAGIR_

Background Information for MED20:


Pubmed-MED20 »
Uniprot-MED20 »
Biogrid-MED20 »
ProteomicsDB-MED20 »

Tumorportal-MED20 »
COSMIC-MED20 »
GenomeRNAi-MED20 »
Genecards-MED20


Protein-protein Interactions for MED20
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BIRC5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCNC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GDF9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LMO2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCL1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TKT Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MED20
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring MED20
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 230 Mediator complex Database 0.76
Category members Corum 300 PC2 complex Database 0.53
Category members Corum 5450 Mediator complex Database 0.45
Category members Corum 301 SMCC complex Database 0.45
Category members Corum 5451 MED18-MED20-MED29 mediator subcomplex Database 0


Categories featuring MED20
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members Pathway Pathway_90 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION 0 0.88
Category members GO Category GO:0016592 mediator complex Database 0.53
Category members GO Category GO:0003899 DNA-directed RNA polymerase activity Database 0.46
Category members Pathway Pathway_41 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION 0 0.35
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0006367 transcription initiation from RNA polymerase II promoter Database 0.25
Category members Pathway Pathway_1 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM 0 0.23
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members Pathway Pathway_822 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY 0 0.09
Category members GO Category GO:0001104 RNA polymerase II transcription cofactor activity Database 0.08
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members GO Category GO:0035914 skeletal muscle cell differentiation Database 0


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