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Query: MCC

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MCC 1 0.999 -1.350 2.680

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MCC Phosphorylation S294 -1.402 -0.640 _LQSVQATGPSS(ph)PGR_
MCC Phosphorylation S405 -5.038 -4.462 _IREFEVETERLNS(ph)R_
MCC Phosphorylation S293 -1.041 _LQSVQATGPS(ph)SPGR_

Background Information for MCC:


Pubmed-MCC »
Uniprot-MCC »
Biogrid-MCC »
ProteomicsDB-MCC »

Tumorportal-MCC »
COSMIC-MCC »
GenomeRNAi-MCC »
Genecards-MCC


Protein-protein Interactions for MCC
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CSNK1E Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC83 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DAB2IP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1967 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAGEE1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NFKBIB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYNC Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MCC
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members USH1C-bd_PDZ_domain IPR019536 0.08
Category members tRNA-bd_arm IPR010978 0.08
Category members EF_hand_dom IPR002048 0


Protein complexes (CORUM database) featuring MCC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5233 TNF-alpha/NF-kappa B signaling complex 5 Database 0.29


Categories featuring MCC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0050680 negative regulation of epithelial cell proliferation Database 0.19
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0016055 Wnt signaling pathway Database 0.11
Category members GO Category GO:0004872 receptor activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0010633 negative regulation of epithelial cell migration Database 0


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