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Query: MARK4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MARK4 0 2.267 0.660 -0.680

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MARK4 Phosphorylation S438 1.483 0.784 _RS(ph)PTSTGEAELKEER_

Background Information for MARK4:


Pubmed-MARK4 »
Uniprot-MARK4 »
Biogrid-MARK4 »
ProteomicsDB-MARK4 »

Tumorportal-MARK4 »
COSMIC-MARK4 »
GenomeRNAi-MARK4 »
Genecards-MARK4


Protein-protein Interactions for MARK4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MANSC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSMC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MARK4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UBA/Ts_N IPR000449 0.34
Category members UBA-like IPR009060 0.17
Category members UBA/transl_elong_EF1B_N_euk IPR015940 0.04
Category members Kinase-like_dom IPR011009 0.03
Category members KA1/Ssp2_C IPR028375 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members KA1_dom IPR001772 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring MARK4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MARK4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0015630 microtubule cytoskeleton Database 1.34
Category members GO Category GO:0043130 ubiquitin binding Database 1.22
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members Pathway Pathway_1142 PID_LKB1_PATHWAY 0 0.6
Category members GO Category GO:0000226 microtubule cytoskeleton organization Database 0.5
Category members GO Category GO:0001578 microtubule bundle formation Database 0.49
Category members GO Category GO:0005815 microtubule organizing center Database 0.39
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0050321 tau-protein kinase activity Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0043015 gamma-tubulin binding Database 0
Category members GO Category GO:0043068 positive regulation of programmed cell death Database 0


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