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Query: MAPK6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MAPK6 1 -5.111 2.490 -0.970 0.892
MAPK6 1 -5.111 2.490 -0.970 -3.989

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MAPK6 Phosphorylation S189 -0.821 -0.414 _GHLS(ph)EGLVTK_
MAPK6 Ubiquitylation K517 -1.941 -0.759 _AQIALEEASQQLAGK(gl)ER_
MAPK6 Ubiquitylation K203 -0.021 -0.779 _APEIMLNSK(gl)GYTK_
MAPK6 Phosphorylation Y187 -0.935 -2.332 _VADPDHDHTGFLTEY(ph)VATR_
MAPK6 Ubiquitylation K480 -1.705 _LIIDLSNWK(gl)EQSK_

Background Information for MAPK6:


Pubmed-MAPK6 »
Uniprot-MAPK6 »
Biogrid-MAPK6 »
ProteomicsDB-MAPK6 »

Tumorportal-MAPK6 »
COSMIC-MAPK6 »
GenomeRNAi-MAPK6 »
Genecards-MAPK6


Protein-protein Interactions for MAPK6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MAPK6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MAPK6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members MAPK_ERK3/4 IPR008350 0.89
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring MAPK6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MAPK6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004707 MAP kinase activity Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_1000 BIOCARTA_MAPK_PATHWAY 0 0
Category members GO Category GO:0000165 MAPK cascade Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0


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