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Query: MAP4K5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MAP4K5 1 1.155 -0.392

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MAP4K5 Ubiquitylation K36 1.547 _VGSGTYGDVYK(gl)AR_

Background Information for MAP4K5:


Pubmed-MAP4K5 »
Uniprot-MAP4K5 »
Biogrid-MAP4K5 »
ProteomicsDB-MAP4K5 »

Tumorportal-MAP4K5 »
COSMIC-MAP4K5 »
GenomeRNAi-MAP4K5 »
Genecards-MAP4K5


Protein-protein Interactions for MAP4K5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDRT15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GRB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAP4K3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MAP4K5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Citron IPR001180 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring MAP4K5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MAP4K5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0007257 activation of JUN kinase activity Database 0.08
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_1000 BIOCARTA_MAPK_PATHWAY 0 0
Category members Pathway Pathway_738 PID_TNF_PATHWAY 0 0
Category members Pathway Pathway_902 BIOCARTA_41BB_PATHWAY 0 0
Category members GO Category GO:0005083 small GTPase regulator activity Database 0
Category members GO Category GO:0008349 MAP kinase kinase kinase kinase activity Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0


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