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Query: MAN2A1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MAN2A1 0 1.100 -0.240 0.680 0.273 0.902

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MAN2A1 Ubiquitylation K638 -0.755 _SQDSLPQK(gl)NIIR_

Background Information for MAN2A1:





Protein-protein Interactions for MAN2A1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FUT8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYZL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MGAT4C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLAUR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTCH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCGB2A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MAN2A1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Glyco_hydro_38_N IPR000602 0
Category members Gal_mutarotase_SF_dom IPR011013 0
Category members Glyco_hydro/deAcase_b/a-brl IPR011330 0
Category members Glyco_hydro_38_C IPR011682 0
Category members Glyco_hydro_38_cen IPR015341 0
Category members Glyco_hydro_57/38_cen IPR028995 0


Protein complexes (CORUM database) featuring MAN2A1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MAN2A1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0001889 liver development Database 0.51
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0007033 vacuole organization Database 0.17
Category members Pathway Pathway_111 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI 0 0.11
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0007585 respiratory gaseous exchange Database 0.08
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members GO Category GO:0050769 positive regulation of neurogenesis Database 0.06
Category members Pathway Pathway_109 KEGG_N_GLYCAN_BIOSYNTHESIS 0 0.04
Category members GO Category GO:0006013 mannose metabolic process Database 0.04
Category members Pathway Pathway_115 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION 0 0
Category members Pathway Pathway_94 REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 0 0
Category members Pathway Pathway_95 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION 0 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds Database 0
Category members GO Category GO:0004559 alpha-mannosidase activity Database 0
Category members GO Category GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity Database 0
Category members GO Category GO:0006491 N-glycan processing Database 0
Category members GO Category GO:0007005 mitochondrion organization Database 0
Category members GO Category GO:0015923 mannosidase activity Database 0
Category members GO Category GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds Database 0
Category members GO Category GO:0018279 protein N-linked glycosylation via asparagine Database 0
Category members GO Category GO:0030246 carbohydrate binding Database 0
Category members GO Category GO:0043687 post-translational protein modification Database 0
Category members GO Category GO:0048286 lung alveolus development Database 0
Category members GO Category GO:0060042 retina morphogenesis in camera-type eye Database 0


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