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Query: LSS

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LSS 0 -0.702 1.920 -0.820 0.985 0.835
LSS 0 -0.702 1.920 -0.820 0.063

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LSS Ubiquitylation K65 -1.467 -1.119 _NYFK(gl)DLPK_
LSS Ubiquitylation K432 -1.819 -1.131 _LSQVPDNPPDYQK(gl)YYR_
LSS Ubiquitylation K506 -1.598 -1.214 _NPDGGFATYETK(gl)R_
LSS Ubiquitylation K15 -1.837 -2.018 _GGPYK(gl)TEPATDLGR_

Background Information for LSS:





Protein-protein Interactions for LSS

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FIP1L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO5C Cat. description Hein, Mann, Cell 2015
Category members IP bait ALOX5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GML Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDDC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PNKD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF10A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LSS

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Terpenoid_cyclase/PrenylTrfase IPR008930 0.04
Category members Prenyltrans IPR001330 0


Protein complexes (CORUM database) featuring LSS

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LSS

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0016866 intramolecular transferase activity Database 0.08
Category members Pathway Pathway_162 KEGG_STEROID_BIOSYNTHESIS 0 0
Category members Pathway Pathway_164 REACTOME_CHOLESTEROL_BIOSYNTHESIS 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members GO Category GO:0005811 lipid particle Database 0
Category members GO Category GO:0006695 cholesterol biosynthetic process Database 0
Category members GO Category GO:0008202 steroid metabolic process Database 0


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