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Query: LRPAP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LRPAP1 0 -0.271 -0.570 0.800
LRPAP1 0 -0.271 -0.570 0.800 -0.311 -0.181

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LRPAP1 Ubiquitylation K65 -0.500 _LNQLWEK(gl)AQR_
LRPAP1 Ubiquitylation K94 -0.080 _IQERDELAWK(gl)K_

Background Information for LRPAP1:





Protein-protein Interactions for LRPAP1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait LCOR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRPAP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LRPAP1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members MG_RAP_rcpt_1 IPR009066 0


Protein complexes (CORUM database) featuring LRPAP1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LRPAP1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0006457 protein folding Database 4.93
Category members GO Category GO:0051082 unfolded protein binding Database 3.74
Category members Pathway Pathway_729 PID_LIS1_PATHWAY 0 1.41
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0008201 heparin binding Database 0.27
Category members GO Category GO:0048237 rough endoplasmic reticulum lumen Database 0.24
Category members GO Category GO:0009986 cell surface Database 0.17
Category members GO Category GO:0048019 receptor antagonist activity Database 0.13
Category members GO Category GO:0032091 negative regulation of protein binding Database 0.08
Category members GO Category GO:0050750 low-density lipoprotein particle receptor binding Database 0.04
Category members GO Category GO:0031982 vesicle Database 0.01
Category members Pathway Pathway_558 PID_REELIN_PATHWAY 0 0.01
Category members Pathway Pathway_594 PID_HEDGEHOG_2PATHWAY 0 0
Category members Disease phenotype Rare_isolated_myopia Rare isolated myopia Database 0
Category members GO Category GO:0004873 asialoglycoprotein receptor activity Database 0
Category members GO Category GO:0010916 negative regulation of very-low-density lipoprotein particle clearance Database 0
Category members GO Category GO:0035473 lipase binding Database 0
Category members GO Category GO:0070326 very-low-density lipoprotein particle receptor binding Database 0


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