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Query: LIN7C

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LIN7C 0 2.172
LIN7C 0 2.172 0.413 0.576 0.542

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LIN7C Ubiquitylation K176 -0.064 0.362 _YTPK(gl)VLEEMESR_
LIN7C Ubiquitylation K161 0.279 0.161 _AVELLK(gl)AAQGK_
LIN7C Ubiquitylation K76 0.092 _ANATAK(gl)ATVAAFAASEGHSHPR_

Background Information for LIN7C:





Protein-protein Interactions for LIN7C

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNB Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF26B Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIN7C Cat. description Hein, Mann, Cell 2015
Category members IP bait MPP6 Cat. description Hein, Mann, Cell 2015
Category members IP bait PXDC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAD18 Cat. description Hein, Mann, Cell 2015
Category members IP bait YAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MPP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MPP5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NSUN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC20A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LIN7C

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members L27 IPR004172 1.84
Category members L27_C IPR014775 0.33
Category members PDZ IPR001478 0.15
Category members Lin-7_homologue IPR017365 0


Protein complexes (CORUM database) featuring LIN7C

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 617 CASK-LIN7C-APBA1 complex Database 0


Categories featuring LIN7C

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members GO Category GO:0005911 cell-cell junction Database 1.4
Category members GO Category GO:0005923 tight junction Database 0.69
Category members GO Category GO:0008092 cytoskeletal protein binding Database 0.5
Category members GO Category GO:0030165 PDZ domain binding Database 0.29
Category members GO Category GO:0006887 exocytosis Database 0.2
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members GO Category GO:0045211 postsynaptic membrane Database 0.06
Category members GO Category GO:0045202 synapse Database 0.06
Category members GO Category GO:0016323 basolateral plasma membrane Database 0.04
Category members GO Category GO:0007269 neurotransmitter secretion Database 0
Category members GO Category GO:0014069 postsynaptic density Database 0


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