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Query: LBR

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LBR 1 6.082 -0.600 0.310 0.658 0.471

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LBR Phosphorylation S99 0.671 0.999 _SAS(ph)ASHQADIK_
LBR Ubiquitylation K183 -0.639 0.960 _LKEIDSK(gl)EEK_
LBR Ubiquitylation K190 -0.968 0.657 _YVAK(gl)ELAVR_
LBR Phosphorylation S128 -0.301 0.481 _LTPLILKPFGNS(ph)ISR_
LBR Phosphorylation S97 0.786 0.479 _RS(ph)ASASHQADIK_
LBR Ubiquitylation K508 0.463 _GANSQK(gl)NAFR_
LBR Phosphorylation S101 0.461 _RSASAS(ph)HQADIK_
LBR Phosphorylation S59 1.927 0.405 _ENDIKPLTS(ph)FR_
LBR Ubiquitylation K601 -0.777 0.355 _YGVAWEK(gl)YCQR_
LBR Phosphorylation S130 -0.662 0.294 _LTPLILKPFGNS(ph)ISR_
LBR Ubiquitylation K178 -0.282 0.282 _LK(gl)EIDSK_
LBR Ubiquitylation K186 -0.551 0.084 _EIDSKEEK(gl)YVAK_
LBR Phosphorylation T58 0.988 -0.034 _ENDIKPLT(ph)SFR_
LBR Phosphorylation S357 -0.097 _NDLS(ph)PASSGNAVYDFFIGR_
LBR Ubiquitylation K107 0.757 -0.107 _SASASHQADIK(gl)EARR_
LBR Ubiquitylation K123 -0.631 _LTPLILK(gl)PFGNSISR_
LBR Ubiquitylation K176 -0.492 _REEVK(gl)LK_
LBR Ubiquitylation K524 -1.353 _LAHLK(gl)TIHTSTGK_

Background Information for LBR:


Pubmed-LBR »
Uniprot-LBR »
Biogrid-LBR »
ProteomicsDB-LBR »

Tumorportal-LBR »
COSMIC-LBR »
GenomeRNAi-LBR »
Genecards-LBR


Protein-protein Interactions for LBR
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C1QBP Cat. description Hein, Mann, Cell 2015
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait MAD2L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait BHLHA15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLEC3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LBR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LUC7L Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LBR
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ergosterol_biosynth_ERG4_ERG24 IPR001171 0.46
Category members Tudor IPR002999 0.28
Category members DUF1295 IPR010721 0.04


Protein complexes (CORUM database) featuring LBR
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LBR
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005635 nuclear envelope Database 7.22
Category members GO Category GO:0031965 nuclear membrane Database 2.59
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0070087 chromo shadow domain binding Database 1.14
Category members GO Category GO:0005521 lamin binding Database 0.75
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0005639 integral to nuclear inner membrane Database 0.35
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0004671 protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity Database 0.18
Category members GO Category GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor Database 0.03
Category members Pathway Pathway_164 REACTOME_CHOLESTEROL_BIOSYNTHESIS 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members GO Category GO:0006481 C-terminal protein methylation Database 0
Category members GO Category GO:0006695 cholesterol biosynthetic process Database 0


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