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bioLOGIC Data

Query: L3MBTL2

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
L3MBTL2	1	0.920	0.230	0.100	-0.842	-0.492	0.272

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
L3MBTL2	Phosphorylation	S67	-0.335	-0.151	_EAGELPTS(ph)PLHLLSPGTPR_
L3MBTL2	Phosphorylation	S689	-0.279	-0.508	_ASS(ph)PELPVSVENIKQETDD_
L3MBTL2	Phosphorylation	S688	-0.105	-0.724	_AS(ph)SPELPVSVENIK_
L3MBTL2	Phosphorylation	S85	1.566		_SLDGSGS(ph)EPAVCEM(ox)CGIVGTR_
L3MBTL2	Ubiquitylation	K105	0.567		_EAFFSK(gl)TK_

Background Information for L3MBTL2:

Pubmed-L3MBTL2 »

Uniprot-L3MBTL2 »

Biogrid-L3MBTL2 »

ProteomicsDB-L3MBTL2 »

Tumorportal-L3MBTL2 »

COSMIC-L3MBTL2 »

GenomeRNAi-L3MBTL2 »

Genecards-L3MBTL2

Protein-protein Interactions for L3MBTL2

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait CBX1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait KLHL22	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait L3MBTL2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait MAX	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait MYO19	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait RING1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait ASB6	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CDH19	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait E2F6	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait HDAC1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait KBTBD7	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait L3MBTL2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait MIER2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait PCGF6	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait PSMC3	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait PSME3	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait RYBP	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait SERPINF1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait WDR5	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait YAF2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in L3MBTL2

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	Znf_FCS	IPR012313	0.31
Category members	Mbt	IPR004092	0

Protein complexes (CORUM database) featuring L3MBTL2

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring L3MBTL2

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0005634	nucleus	Database	INF
Category members	GO Category	GO:0006351	transcription, DNA-templated	Database	1.07
Category members	GO Category	GO:0042393	histone binding	Database	0.94
Category members	GO Category	GO:0035064	methylated histone residue binding	Database	0.53
Category members	GO Category	GO:0008270	zinc ion binding	Database	0.29
Category members	GO Category	GO:0016568	chromatin modification	Database	0.18
Category members	GO Category	GO:0003714	transcription corepressor activity	Database	0
Category members	GO Category	GO:0006355	regulation of transcription, DNA-dependent	Database	0