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Query: KPNA3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KPNA3 0 1.630 -0.380 0.240 0.631 -0.390 0.376 0.651 -0.147

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KPNA3 Phosphorylation S56 0.255 _NVPQEES(ph)LEDSDVDADFK_
KPNA3 Phosphorylation S60 0.014 0.081 _RNVPQEESLEDS(ph)DVDADFK_

Background Information for KPNA3:


Pubmed-KPNA3 »
Uniprot-KPNA3 »
Biogrid-KPNA3 »
ProteomicsDB-KPNA3 »

Tumorportal-KPNA3 »
COSMIC-KPNA3 »
GenomeRNAi-KPNA3 »
Genecards-KPNA3


Protein-protein Interactions for KPNA3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C10orf12 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF22 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIFC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KPNB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MTA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait NCBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NCBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP107 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP153 Cat. description Hein, Mann, Cell 2015
Category members IP bait RANBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RCC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait B2M Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IER2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIF22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MECP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RCC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KPNA3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members HEAT IPR000357 3.83
Category members Armadillo IPR000225 1.58
Category members Importin-a_IBB IPR002652 0.44


Protein complexes (CORUM database) featuring KPNA3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1728 CTCF-nucleophosmin-PARP-HIS-KPNA-LMNA-TOP complex Database 0.63
Category members Corum 5193 TNF-alpha/NF-kappa B signaling complex (CHUK, KPNA3, NFKB2, NFKBIB, REL, IKBKG, NFKB1, NFKBIE, RELB, NFKBIA, RELA, TNIP2) Database 0.03


Categories featuring KPNA3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0005643 nuclear pore Database 6.58
Category members Pathway Pathway_689 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES 0 3.51
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0006606 protein import into nucleus Database 1.81
Category members GO Category GO:0006607 NLS-bearing protein import into nucleus Database 1.48
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members Pathway Pathway_699 REACTOME_INTERFERON_SIGNALING 0 0.86
Category members GO Category GO:0006461 protein complex assembly Database 0.57
Category members GO Category GO:0019221 cytokine-mediated signaling pathway Database 0.44
Category members Pathway Pathway_505 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 0 0.33
Category members GO Category GO:0008565 protein transporter activity Database 0.26
Category members GO Category GO:0046718 viral entry into host cell Database 0.04
Category members GO Category GO:0008139 nuclear localization sequence binding Database 0


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