bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: KPNA1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KPNA1 0 -1.035 0.300 -0.080 -0.148 -0.215 0.756 -0.024 -0.936

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KPNA1 Ubiquitylation K46 -0.562 -0.121 _EEQLFK(gl)R_

Background Information for KPNA1:


Pubmed-KPNA1 »
Uniprot-KPNA1 »
Biogrid-KPNA1 »
ProteomicsDB-KPNA1 »

Tumorportal-KPNA1 »
COSMIC-KPNA1 »
GenomeRNAi-KPNA1 »
Genecards-KPNA1


Protein-protein Interactions for KPNA1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDKN2AIP Cat. description Hein, Mann, Cell 2015
Category members IP bait CHD8 Cat. description Hein, Mann, Cell 2015
Category members IP bait KPNA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KPNB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP153 Cat. description Hein, Mann, Cell 2015
Category members IP bait PHAX Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP50 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNMT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SREK1IP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KPNA1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members HEAT IPR000357 3.83
Category members Armadillo IPR000225 1.58
Category members Importin-a_IBB IPR002652 0.44


Protein complexes (CORUM database) featuring KPNA1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1728 CTCF-nucleophosmin-PARP-HIS-KPNA-LMNA-TOP complex Database 0.63


Categories featuring KPNA1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_371 REACTOME_INFLUENZA_LIFE_CYCLE 0 INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members GO Category GO:0019058 viral life cycle Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_197 REACTOME_HIV_INFECTION 0 12.07
Category members Pathway Pathway_196 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS 0 9.67
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members Pathway Pathway_1310 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS 0 7.24
Category members Pathway Pathway_1206 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS 0 6.87
Category members GO Category GO:0005643 nuclear pore Database 6.58
Category members Pathway Pathway_689 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES 0 3.51
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0006921 cellular component disassembly involved in execution phase of apoptosis Database 2.98
Category members Pathway Pathway_934 PID_PI3KCI_AKT_PATHWAY 0 2.5
Category members Pathway Pathway_876 REACTOME_APOPTOTIC_EXECUTION_PHASE 0 2.5
Category members Pathway Pathway_837 REACTOME_APOPTOSIS 0 2.39
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0006606 protein import into nucleus Database 1.81
Category members GO Category GO:0006607 NLS-bearing protein import into nucleus Database 1.48
Category members Pathway Pathway_699 REACTOME_INTERFERON_SIGNALING 0 0.86
Category members Pathway Pathway_955 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION 0 0.51
Category members GO Category GO:0000018 regulation of DNA recombination Database 0.5
Category members GO Category GO:0019221 cytokine-mediated signaling pathway Database 0.44
Category members Pathway Pathway_505 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 0 0.33
Category members GO Category GO:0030425 dendrite Database 0.26
Category members GO Category GO:0006309 apoptotic DNA fragmentation Database 0.26
Category members GO Category GO:0008565 protein transporter activity Database 0.26
Category members GO Category GO:0008139 nuclear localization sequence binding Database 0
Category members GO Category GO:0042307 positive regulation of protein import into nucleus Database 0


.

© Copyright Svejstrup Laboratory 2015