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Query: KIF1A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KIF1A 0 3.798 0.540 -0.550 0.715 -0.651
KIF1A 0 3.798 0.540 -0.550 0.592

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KIF1A Ubiquitylation K1563 -5.831 1.045 _ELAVK(gl)CLR_
KIF1A Phosphorylation S1477 0.580 0.528 _S(ph)DSLILDHQWELEK_
KIF1A Phosphorylation S425 0.226 0.513 _AAS(ph)VSSLHER_
KIF1A Phosphorylation S1479 0.245 0.345 _SDS(ph)LILDHQWELEK_
KIF1A Phosphorylation S428 0.256 _AASVSS(ph)LHER_
KIF1A Phosphorylation S1446 0.354 0.201 _VTGVYELSLCHVADAGS(ph)PGMQR_
KIF1A Ubiquitylation K243 0.567 0.154 _VSK(gl)ISLVDLAGSER_
KIF1A Ubiquitylation K1011 -1.711 -0.039 _QSGTAK(gl)ISFDDQHFEK_
KIF1A Phosphorylation S1602 0.026 -0.209 _DPS(ph)MSPLGVATLTPSSTCPSLVEGR_
KIF1A Phosphorylation S1604 -0.266 _DPSMS(ph)PLGVATLTPSSTCPSLVEGR_
KIF1A Ubiquitylation K754 -1.146 -0.455 _EANAISVELKK(gl)_
KIF1A Ubiquitylation K977 -0.660 -0.529 _VAIVSEK(gl)GEVK_
KIF1A Phosphorylation S1195 -0.738 -0.620 _DVLS(ph)PLRPSR_
KIF1A Phosphorylation S1641 -1.145 -1.108 _PAS(ph)PEPELLPEADSK_
KIF1A Ubiquitylation K1687 -1.299 _VSPIVSK(gl)K_
KIF1A Ubiquitylation K1688 -1.299 _VSPIVSK(gl)K_
KIF1A Ubiquitylation K685 -0.482 -1.308 _LEALQK(gl)QMDSR_
KIF1A Ubiquitylation K1140 -1.790 -1.571 _HDEAFSTEPLK(gl)NTGR_
KIF1A Ubiquitylation K373 0.989 _ELK(gl)DEVTR_
KIF1A Ubiquitylation K753 -0.683 _EANAISVELK(gl)K_

Background Information for KIF1A:


Pubmed-KIF1A »
Uniprot-KIF1A »
Biogrid-KIF1A »
ProteomicsDB-KIF1A »

Tumorportal-KIF1A »
COSMIC-KIF1A »
GenomeRNAi-KIF1A »
Genecards-KIF1A


Protein-protein Interactions for KIF1A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AARSD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CETN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DOCK5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DQX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM19A3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1279 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIF1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDDC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSMC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF166 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM35 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KIF1A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members FHA_dom IPR000253 2.3
Category members Kinesin-like IPR022164 0.94
Category members SMAD_FHA_domain IPR008984 0.86
Category members KIF1B IPR022140 0.39
Category members PH_domain IPR001849 0.14
Category members C2_dom IPR000008 0
Category members Kinesin_motor_dom IPR001752 0


Protein complexes (CORUM database) featuring KIF1A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring KIF1A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members GO Category GO:0007018 microtubule-based movement Database 0.75
Category members GO Category GO:0003777 microtubule motor activity Database 0.49
Category members GO Category GO:0005871 kinesin complex Database 0.27
Category members GO Category GO:0003774 motor activity Database 0.2
Category members Disease phenotype Hereditary_sensory_and_autonomic_neuropathy_type_2 Hereditary sensory and autonomic neuropathy type 2 Database 0.09
Category members Disease phenotype Autosomal_dominant_non-syndromic_intellectual_disability Autosomal dominant non-syndromic intellectual disability Database 0.08
Category members GO Category GO:0008219 cell death Database 0.08
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members GO Category GO:0008089 anterograde axon cargo transport Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0


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