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Query: KHSRP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KHSRP 1 1.807 0.130 -0.080 -1.346 -0.756 -1.217 -1.712 -0.497

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KHSRP Phosphorylation S125 1.265 1.949 _KLAS(ph)QGDSISSQLGPIHPPPR_
KHSRP Phosphorylation S274 -0.095 1.644 _MILIQDGS(ph)QNTNVDKPLR_
KHSRP Phosphorylation T277 0.126 1.450 _MILIQDGSQNT(ph)NVDKPLR_
KHSRP Ubiquitylation K251 0.622 1.298 _AGLVIGK(gl)GGETIK_
KHSRP Ubiquitylation K257 0.850 1.240 _GGETIK(gl)QLQER_
KHSRP Ubiquitylation K628 0.007 0.744 _K(gl)IGQQPQQPGAPPQQDYTK_
KHSRP Phosphorylation S181 0.331 0.424 _VQIS(ph)PDSGGLPER_
KHSRP Ubiquitylation K205 0.356 _SVSLTGAPESVQKAK(gl)_
KHSRP Ubiquitylation K109 -0.384 0.232 _IGGDAATTVNNSTPDFGFGGQK(gl)R_
KHSRP Phosphorylation S480 0.929 -0.004 _LFIIRGS(ph)PQQIDHAK_
KHSRP Ubiquitylation K177 -0.480 -0.130 _IQQDSGCK(gl)VQISPDSGGLPER_
KHSRP Ubiquitylation K122 -0.502 -1.429 _QLEDGDQPESKK(gl)_
KHSRP Phosphorylation T100 0.619 _IGGDAATTVNNST(ph)PDFGFGGQK_
KHSRP Ubiquitylation K169 0.608 _GGEQINK(gl)IQQDSGCK_
KHSRP Ubiquitylation K203 0.612 _SVSLTGAPESVQK(gl)AK_
KHSRP Ubiquitylation K359 -0.109 _IQFK(gl)QDDGTGPEK_

Background Information for KHSRP:


Pubmed-KHSRP »
Uniprot-KHSRP »
Biogrid-KHSRP »
ProteomicsDB-KHSRP »

Tumorportal-KHSRP »
COSMIC-KHSRP »
GenomeRNAi-KHSRP »
Genecards-KHSRP


Protein-protein Interactions for KHSRP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MKNK2 Cat. description Hein, Mann, Cell 2015


Protein Domains in KHSRP
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members KH_dom_type_2 IPR004044 0.34
Category members KH_dom IPR004087 0.23
Category members KH_dom_type_1 IPR004088 0.13
Category members DUF1897 IPR015096 0


Protein complexes (CORUM database) featuring KHSRP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring KHSRP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members Pathway Pathway_773 REACTOME_METABOLISM_OF_MRNA 0 INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0016071 mRNA metabolic process Database INF
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members Pathway Pathway_781 REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS 0 2.04
Category members GO Category GO:0051028 mRNA transport Database 1.7
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0010494 cytoplasmic stress granule Database 1.32
Category members Pathway Pathway_147 REACTOME_UNFOLDED_PROTEIN_RESPONSE 0 1.08
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0000375 RNA splicing, via transesterification reactions Database 0.73
Category members Pathway Pathway_392 REACTOME_PERK_REGULATED_GENE_EXPRESSION 0 0.64
Category members Pathway Pathway_146 REACTOME_DIABETES_PATHWAYS 0 0.39
Category members Pathway Pathway_391 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 0 0.23
Category members Pathway Pathway_847 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP 0 0.04
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


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