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Query: KDM2B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KDM2B 1 3.824 -0.080 -0.260
KDM2B 1 3.824 -0.080 -0.260 0.216 0.247

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KDM2B Phosphorylation S394 1.119 1.347 _ELS(ph)KELNHEIQR_
KDM2B Phosphorylation S458 1.030 _HQLGPS(ph)LRSPPR_
KDM2B Phosphorylation S461 0.284 _HQLGPSLRS(ph)PPR_
KDM2B Phosphorylation S14 -0.285 -0.121 _(ac)AMSVSAEDDDYES(ph)EPDQNR_
KDM2B Phosphorylation S357 -0.521 -0.434 _SSS(ph)PTAGPSTEGAEGPEEK_
KDM2B Ubiquitylation K129 -0.632 _DVK(gl)LLVGSR_
KDM2B Phosphorylation S472 -0.918 -1.112 _VISRPPPS(ph)VSPPK_
KDM2B Phosphorylation S474 -0.740 -1.153 _VISRPPPSVS(ph)PPK_
KDM2B Phosphorylation S443 2.646 _APKPPTDGS(ph)TSPTSTPSEDQEALGK_

Background Information for KDM2B:


Pubmed-KDM2B »
Uniprot-KDM2B »
Biogrid-KDM2B »
ProteomicsDB-KDM2B »

Tumorportal-KDM2B »
COSMIC-KDM2B »
GenomeRNAi-KDM2B »
Genecards-KDM2B


Protein-protein Interactions for KDM2B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BCOR Cat. description Hein, Mann, Cell 2015
Category members IP bait PCGF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RNF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SKP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RYBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YAF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KDM2B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_FYVE_PHD IPR011011 1.23
Category members Znf_PHD IPR001965 1.15
Category members Znf_PHD-finger IPR019787 0.91
Category members F-box_dom IPR001810 0
Category members Znf_CXXC IPR002857 0
Category members JmjC_dom IPR003347 0
Category members Leu-rich_rpt_Cys-con_subtyp IPR006553 0


Protein complexes (CORUM database) featuring KDM2B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1178 BCOR complex Database 0.34


Categories featuring KDM2B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0032452 histone demethylase activity Database 0.66
Category members GO Category GO:0043524 negative regulation of neuron apoptotic process Database 0.66
Category members GO Category GO:0031519 PcG protein complex Database 0.62
Category members GO Category GO:0019843 rRNA binding Database 0.46
Category members GO Category GO:0035518 histone H2A monoubiquitination Database 0.34
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0021592 fourth ventricle development Database 0.13
Category members GO Category GO:0021678 third ventricle development Database 0.07
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0030902 hindbrain development Database 0.02
Category members GO Category GO:0048596 embryonic camera-type eye morphogenesis Database 0.01
Category members GO Category GO:0007283 spermatogenesis Database 0
Category members GO Category GO:0016577 histone demethylation Database 0
Category members GO Category GO:0021555 midbrain-hindbrain boundary morphogenesis Database 0
Category members GO Category GO:0021670 lateral ventricle development Database 0
Category members GO Category GO:0030900 forebrain development Database 0
Category members GO Category GO:0030901 midbrain development Database 0
Category members GO Category GO:0051864 histone demethylase activity (H3-K36 specific) Database 0


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