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Query: KCNJ8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KCNJ8 1 4.755 -2.110 4.400

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KCNJ8 Ubiquitylation K48 0.355 _SGACNLAHK(gl)NIR_
KCNJ8 Ubiquitylation K347 -0.233 _FGNTVK(gl)VAAPR_

Background Information for KCNJ8:


Pubmed-KCNJ8 »
Uniprot-KCNJ8 »
Biogrid-KCNJ8 »
ProteomicsDB-KCNJ8 »

Tumorportal-KCNJ8 »
COSMIC-KCNJ8 »
GenomeRNAi-KCNJ8 »
Genecards-KCNJ8


Protein-protein Interactions for KCNJ8
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ADAM33 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD1E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HLA-DQA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MCOLN3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NAALADL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait P2RX4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLXDC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCTN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMED6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KCNJ8
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ig_E-set IPR014756 0
Category members K_chnl_inward-rec_Kir IPR016449 0


Protein complexes (CORUM database) featuring KCNJ8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring KCNJ8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0017098 sulfonylurea receptor binding Database 0.65
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0042383 sarcolemma Database 0.36
Category members GO Category GO:0032496 response to lipopolysaccharide Database 0.35
Category members GO Category GO:0042311 vasodilation Database 0.29
Category members GO Category GO:0008076 voltage-gated potassium channel complex Database 0.27
Category members Pathway Pathway_760 REACTOME_POTASSIUM_CHANNELS 0 0.23
Category members GO Category GO:0007268 synaptic transmission Database 0.23
Category members GO Category GO:0006813 potassium ion transport Database 0.11
Category members GO Category GO:0051607 defense response to virus Database 0.07
Category members GO Category GO:0009268 response to pH Database 0.01
Category members Pathway Pathway_139 REACTOME_NEURONAL_SYSTEM 0 0
Category members Pathway Pathway_761 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS 0 0
Category members Disease phenotype BRUGADA_SYNDROME BRUGADA SYNDROME Database 0
Category members Disease phenotype SUDDEN_INFANT_DEATH_SYNDROME SUDDEN INFANT DEATH SYNDROME Database 0
Category members GO Category GO:0001822 kidney development Database 0
Category members GO Category GO:0005242 inward rectifier potassium channel activity Database 0
Category members GO Category GO:0007507 heart development Database 0
Category members GO Category GO:0008282 ATP-sensitive potassium channel complex Database 0
Category members GO Category GO:0010107 potassium ion import Database 0
Category members GO Category GO:0015272 ATP-activated inward rectifier potassium channel activity Database 0
Category members GO Category GO:0030016 myofibril Database 0
Category members GO Category GO:0043330 response to exogenous dsRNA Database 0


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