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Query: KANK1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KANK1 0 1.133 0.160 -0.720

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KANK1 Phosphorylation S325 0.481 0.652 _SYS(ph)AGNASQLEQLSR_

Background Information for KANK1:


Pubmed-KANK1 »
Uniprot-KANK1 »
Biogrid-KANK1 »
ProteomicsDB-KANK1 »

Tumorportal-KANK1 »
COSMIC-KANK1 »
GenomeRNAi-KANK1 »
Genecards-KANK1


Protein-protein Interactions for KANK1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DYNLL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF21A Cat. description Hein, Mann, Cell 2015
Category members IP bait ARRB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIP4K2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KANK1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ankyrin_rpt IPR002110 0
Category members Ankyrin_rpt-contain_dom IPR020683 0
Category members KN_motif IPR021939 0


Protein complexes (CORUM database) featuring KANK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring KANK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0030336 negative regulation of cell migration Database 0.85
Category members GO Category GO:0032587 ruffle membrane Database 0.65
Category members GO Category GO:0008013 beta-catenin binding Database 0.35
Category members GO Category GO:0030837 negative regulation of actin filament polymerization Database 0.13
Category members GO Category GO:0035024 negative regulation of Rho protein signal transduction Database 0.06
Category members GO Category GO:0010977 negative regulation of neuron projection development Database 0.04
Category members Disease phenotype Inherited_congenital_spastic_tetraplegia Inherited congenital spastic tetraplegia Database 0.04
Category members GO Category GO:0035413 positive regulation of catenin import into nucleus Database 0.02
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0030177 positive regulation of Wnt signaling pathway Database 0
Category members GO Category GO:0046627 negative regulation of insulin receptor signaling pathway Database 0


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