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Query: HSPA6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HSPA6 0 0.390 0.130 -0.260 -0.018 0.333 0.022 0.090
HSPA6 0 0.390 0.130 -0.260 -0.061

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HSPA6 Ubiquitylation K359 0.339 _LLQDFFNGK(gl)ELNK_

Background Information for HSPA6:


Pubmed-HSPA6 »
Uniprot-HSPA6 »
Biogrid-HSPA6 »
ProteomicsDB-HSPA6 »

Tumorportal-HSPA6 »
COSMIC-HSPA6 »
GenomeRNAi-HSPA6 »
Genecards-HSPA6


Protein-protein Interactions for HSPA6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HNRNPD Cat. description Hein, Mann, Cell 2015
Category members IP bait SGTB Cat. description Hein, Mann, Cell 2015
Category members IP bait SIDT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ABHD15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSPBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ILK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHL34 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MOCS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NTNG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POC1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRODH Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TTC30B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VILL Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HSPA6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members HSP70_C IPR029048 0.66
Category members HSP70_peptide-bd IPR029047 0.55
Category members MreB_Mrl IPR004753 0.4
Category members Hsp_70_fam IPR013126 0.4


Protein complexes (CORUM database) featuring HSPA6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HSPA6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0008180 COP9 signalosome Database 1.47
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members GO Category GO:0006986 response to unfolded protein Database 0.62
Category members Pathway Pathway_767 KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION 0 0.09
Category members Pathway Pathway_715 KEGG_MAPK_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0000902 cell morphogenesis Database 0


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