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Query: HPS4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HPS4 0 0.478 0.980 -0.680

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HPS4 Phosphorylation S272 0.478 _SLAS(ph)PAGLQDGSAQHHPK_

Background Information for HPS4:





Protein-protein Interactions for HPS4

Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in HPS4

Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring HPS4

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 11 BLOC-3 (biogenesis of lysosome-related organelles complex 3) Database 0
Category members Corum 241 BLOC-3 (biogenesis of lysosome-related organelles complex 3) Database 0


Categories featuring HPS4

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0042470 melanosome Database 5.59
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0006605 protein targeting Database 0.29
Category members GO Category GO:0016023 cytoplasmic membrane-bounded vesicle Database 0.17
Category members GO Category GO:0050821 protein stabilization Database 0.04
Category members Disease phenotype Hermansky-Pudlak_syndrome_with_pulmonary_fibrosis Hermansky-Pudlak syndrome with pulmonary fibrosis Database 0
Category members GO Category GO:0005764 lysosome Database 0
Category members GO Category GO:0006996 organelle organization Database 0
Category members GO Category GO:0007040 lysosome organization Database 0
Category members GO Category GO:0007599 hemostasis Database 0
Category members GO Category GO:0030318 melanocyte differentiation Database 0
Category members GO Category GO:0031085 BLOC-3 complex Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0046983 protein dimerization activity Database 0


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