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Query: HNRNPM

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HNRNPM 2 6.468 0.210 -0.550 -0.689 -1.927 -0.440 -0.803 -0.188

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HNRNPM Ubiquitylation K651 1.734 1.372 _K(gl)ACQIFVR_
HNRNPM Phosphorylation S575 0.835 1.331 _MGANS(ph)LER_
HNRNPM Ubiquitylation K381 1.140 1.108 _INEILSNALK(gl)R_
HNRNPM Ubiquitylation K716 0.926 0.990 _MMNGMK(gl)LSGR_
HNRNPM Phosphorylation S528 1.314 0.912 _MGLS(ph)MER_
HNRNPM Ubiquitylation K88 0.540 0.868 _WQSLK(gl)DLVK_
HNRNPM Phosphorylation S618 1.486 0.753 _MGLAMGGGGGAS(ph)FDR_
HNRNPM Ubiquitylation K388 0.534 0.382 _RGEIIAK(gl)QGGGGGGGSVPGIER_
HNRNPM Ubiquitylation K698 0.670 0.201 _GCGVVK(gl)FESPEVAER_
HNRNPM Ubiquitylation K242 -0.071 -0.112 _ADILEDKDGK(gl)SR_
HNRNPM Ubiquitylation K69 -0.327 -0.144 _GGNRFEPYANPTK(gl)R_
HNRNPM Phosphorylation S701 -0.135 -0.167 _FES(ph)PEVAER_
HNRNPM Ubiquitylation K134 0.163 _AAEVLNK(gl)HSLSGRPLK_
HNRNPM Ubiquitylation K239 0.592 _ADILEDK(gl)DGK_
HNRNPM Phosphorylation S452 3.711 _MGS(ph)GIER_

Background Information for HNRNPM:


Pubmed-HNRNPM »
Uniprot-HNRNPM »
Biogrid-HNRNPM »
ProteomicsDB-HNRNPM »

Tumorportal-HNRNPM »
COSMIC-HNRNPM »
GenomeRNAi-HNRNPM »
Genecards-HNRNPM


Protein-protein Interactions for HNRNPM
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AKAP8 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC9 Cat. description Hein, Mann, Cell 2015
Category members IP bait FUS Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA3 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPF Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPH2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MATR3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MGP Cat. description Hein, Mann, Cell 2015
Category members IP bait MYEF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PTBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC16A Cat. description Hein, Mann, Cell 2015


Protein Domains in HNRNPM
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34


Protein complexes (CORUM database) featuring HNRNPM
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3055 Nop56p-associated pre-rRNA complex Database INF
Category members Corum 1181 C complex spliceosome Database 2.39
Category members Corum 1332 Large Drosha complex Database 0.08


Categories featuring HNRNPM
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005681 spliceosomal complex Database 3.88
Category members GO Category GO:0071013 catalytic step 2 spliceosome Database 2.28
Category members GO Category GO:0016363 nuclear matrix Database 1.89
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0000380 alternative mRNA splicing, via spliceosome Database 0.29
Category members GO Category GO:0042382 paraspeckles Database 0.23


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