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Query: HNRNPL

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HNRNPL 0 1.698 -0.170 0.370 -0.430 -0.816 -0.279 -0.040 0.131
HNRNPL 0 1.698 -0.170 0.370 -0.409 -1.131 -0.511

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HNRNPL Ubiquitylation K493 1.062 0.580 _FSTPEQAAK(gl)NR_
HNRNPL Ubiquitylation K269 0.860 0.261 _IEYAK(gl)PTR_
HNRNPL Ubiquitylation K538 -0.280 0.255 _VFSGK(gl)SER_
HNRNPL Ubiquitylation K3 0.579 _VK(gl)MAAAGGGGGGGR_
HNRNPL Ubiquitylation K59 0.308 _YYGGGSEGGRAPK(gl)R_
HNRNPL Ubiquitylation K302 -0.616 _NDQDTWDYTNPNLSGQGDPGSNPNK(gl)R_
HNRNPL Ubiquitylation K455 -0.114 _LNVCVSK(gl)QPAIMPGQSYGLEDGSCSYK_
HNRNPL Ubiquitylation K533 1.067 _RPSSVK(gl)VFSGK_

Background Information for HNRNPL:


Pubmed-HNRNPL »
Uniprot-HNRNPL »
Biogrid-HNRNPL »
ProteomicsDB-HNRNPL »

Tumorportal-HNRNPL »
COSMIC-HNRNPL »
GenomeRNAi-HNRNPL »
Genecards-HNRNPL


Protein-protein Interactions for HNRNPL
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EIF3I Cat. description Hein, Mann, Cell 2015
Category members IP bait FUS Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait MATR3 Cat. description Hein, Mann, Cell 2015
Category members IP bait APOBEC3D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELAVL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HNRNPL
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members HnRNP-L_PTB IPR006536 0


Protein complexes (CORUM database) featuring HNRNPL
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5615 Emerin complex 52 Database 0.99


Categories featuring HNRNPL
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0030529 ribonucleoprotein complex Database 8.45
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0019013 viral nucleocapsid Database 0.55
Category members GO Category GO:0006396 RNA processing Database 0.17
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0


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