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Query: HNRNPD

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HNRNPD 1 6.000 -0.108
HNRNPD 1 6.000 0.043 -0.543 -0.123 0.230 0.323

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HNRNPD Ubiquitylation K114 1.183 2.839 _DLK(gl)DYFSK_
HNRNPD Ubiquitylation K255 1.330 0.804 _CEIK(gl)VAMSK_
HNRNPD Phosphorylation S71 0.207 0.564 _IDAS(ph)KNEEDEGHSNSSPR_
HNRNPD Phosphorylation S82 0.468 0.491 _IDASKNEEDEGHSNS(ph)SPR_
HNRNPD Phosphorylation S83 0.540 0.447 _IDASKNEEDEGHSNSS(ph)PR_
HNRNPD Phosphorylation S190 0.067 0.142 _IFVGGLS(ph)PDTPEEK_
HNRNPD Ubiquitylation K197 0.079 0.081 _IFVGGLSPDTPEEK(gl)IR_
HNRNPD Ubiquitylation K260 0.443 -1.116 _VAMSK(gl)EQYQQQQQWGSR_
HNRNPD Ubiquitylation K72 -0.128 _IDASK(gl)NEEDEGHSNSSPR_
HNRNPD Ubiquitylation K111 1.461 _MFIGGLSWDTTKK(gl)_
HNRNPD Ubiquitylation K129 -0.154 _FGEVVDCTLK(gl)LDPITGR_
HNRNPD Ubiquitylation K165 0.293 _LNGK(gl)VIDPK_
HNRNPD Ubiquitylation K251 0.873 _YHNVGLSK(gl)CEIK_

Background Information for HNRNPD:


Pubmed-HNRNPD »
Uniprot-HNRNPD »
Biogrid-HNRNPD »
ProteomicsDB-HNRNPD »

Tumorportal-HNRNPD »
COSMIC-HNRNPD »
GenomeRNAi-HNRNPD »
Genecards-HNRNPD


Protein-protein Interactions for HNRNPD
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DYNC1H1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPD Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPH2 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait MYEF2 Cat. description Hein, Mann, Cell 2015


Protein Domains in HNRNPD
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members CARG-binding_factor_N IPR012956 0.21


Protein complexes (CORUM database) featuring HNRNPD
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1307 Multiprotein complex (mRNA turnover) Database 0.21
Category members Corum 1308 PABPC1-HSPA8-HNRPD-EIF4G1 complex Database 0.04
Category members Corum 1306 PIN1-AUF1 complex Database 0


Categories featuring HNRNPD
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members Pathway Pathway_773 REACTOME_METABOLISM_OF_MRNA 0 INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0016071 mRNA metabolic process Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0030529 ribonucleoprotein complex Database 8.45
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members Pathway Pathway_781 REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS 0 2.04
Category members Pathway Pathway_776 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 0 1.45
Category members GO Category GO:0042162 telomeric DNA binding Database 1.23
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0019013 viral nucleocapsid Database 0.55
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0006396 RNA processing Database 0.17
Category members GO Category GO:0043488 regulation of mRNA stability Database 0.07
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006401 RNA catabolic process Database 0


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