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Query: HNRNPC

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HNRNPC 2 6.827
HNRNPC 2 6.827 -1.880
HNRNPC 2 6.827 0.328
HNRNPC 2 6.827 0.393 -0.963 -0.202

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HNRNPC Ubiquitylation K189 2.864 2.924 _LK(gl)GDDLQAIKK_
HNRNPC Ubiquitylation K39 1.567 1.654 _KSDVEAIFSK(gl)YGK_
HNRNPC Ubiquitylation K223 2.087 1.452 _EQSK(gl)QAVEMK_
HNRNPC Ubiquitylation K8 0.732 1.200 _(ac)ASNVTNK(gl)TDPR_
HNRNPC Phosphorylation S219 1.346 1.180 _NDKS(ph)EEEQSSSSVKK_
HNRNPC Ubiquitylation K204 1.166 1.091 _ELTQIK(gl)QK_
HNRNPC Ubiquitylation K198 1.950 1.082 _K(gl)ELTQIK_
HNRNPC Ubiquitylation K42 1.682 0.918 _YGK(gl)IVGCSVHK_
HNRNPC Phosphorylation S240 0.895 0.581 _M(ox)ES(ph)EGGADDSAEEGDLLDDDDNEDR_
HNRNPC Ubiquitylation K30 1.835 0.526 _K(gl)SDVEAIFSK_
HNRNPC Phosphorylation S247 0.551 0.433 _MESEGGADDS(ph)AEEGDLLDDDDNEDRGDDQVK_
HNRNPC Ubiquitylation K29 0.547 0.408 _VFIGNLNTLVVK(gl)K_
HNRNPC Phosphorylation S285 0.568 0.403 _EAEEGEDDRDS(ph)ANGEDDS_
HNRNPC Phosphorylation S246 0.479 0.284 _M(ox)ESEGGADDS(ph)AEEGDLLDDDDNEDR_
HNRNPC Phosphorylation S239 0.162 _M(ox)ES(ph)EGGADDSAEEGDLLDDDDNEDR_
HNRNPC Phosphorylation S227 -0.159 -0.194 _SEEEQSSSS(ph)VKKDETNVK_
HNRNPC Phosphorylation S115 0.163 -0.604 _SAAEMYGSVTEHPSPS(ph)PLLSSSFDLDYDFQR_
HNRNPC Ubiquitylation K89 2.190 _MIAGQVLDINLAAEPK(gl)VNR_
HNRNPC Ubiquitylation K187 2.283 _SGK(gl)LKGDDLQAIK_
HNRNPC Ubiquitylation K206 1.658 _QK(gl)VDSLLENLEK_
HNRNPC Ubiquitylation K229 0.976 _QAVEMK(gl)NDKSEEEQSSSSVK_
HNRNPC Ubiquitylation K232 1.213 _QAVEMK(gl)NDKSEEEQSSSSVK_
HNRNPC Ubiquitylation K243 -0.143 _NDKSEEEQSSSSVK(gl)KDETNVK_
HNRNPC Phosphorylation S253 0.514 _M(ox)ES(ph)EGGADDS(ph)AEEGGLLDDDDNEDRGDDQLELIK_
HNRNPC Phosphorylation S260 0.514 _M(ox)ES(ph)EGGADDS(ph)AEEGGLLDDDDNEDRGDDQLELIK_

Background Information for HNRNPC:


Pubmed-HNRNPC »
Uniprot-HNRNPC »
Biogrid-HNRNPC »
ProteomicsDB-HNRNPC »

Tumorportal-HNRNPC »
COSMIC-HNRNPC »
GenomeRNAi-HNRNPC »
Genecards-HNRNPC


Protein-protein Interactions for HNRNPC
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCDC93 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP55 Cat. description Hein, Mann, Cell 2015
Category members IP bait ENTHD2 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA3 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPD Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait MATR3 Cat. description Hein, Mann, Cell 2015
Category members IP bait NLRP3 Cat. description Hein, Mann, Cell 2015
Category members IP bait TAF15 Cat. description Hein, Mann, Cell 2015
Category members IP bait APOBEC3D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C11orf57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELAVL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXW11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GSPT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ILF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MTMR7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HNRNPC
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members hnRNP_C_Raly IPR017347 0.89
Category members Regulat_G_prot_signal_superfam IPR016137 0.05


Protein complexes (CORUM database) featuring HNRNPC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 778 LARC complex (LCR-associated remodeling complex) Database 5.04
Category members Corum 1181 C complex spliceosome Database 2.39
Category members Corum 924 Toposome Database 0.88


Categories featuring HNRNPC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0030529 ribonucleoprotein complex Database 8.45
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005681 spliceosomal complex Database 3.88
Category members Pathway Pathway_881 PID_TELOMERASE_PATHWAY 0 2.64
Category members GO Category GO:0071013 catalytic step 2 spliceosome Database 2.28
Category members GO Category GO:0003729 mRNA binding Database 1.38
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0019013 viral nucleocapsid Database 0.55
Category members GO Category GO:0045120 pronucleus Database 0.27
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0038032 termination of G-protein coupled receptor signaling pathway Database 0.05


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