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Query: HIST3H2BB

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HIST3H2BB 1 2.154
HIST3H2BB 1 2.154 -0.620 0.066 0.702

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HIST3H2BB Ubiquitylation K117 0.346 1.538 _HAVSEGTK(gl)AVTK_
HIST3H2BB Ubiquitylation K109 0.117 0.362 _LLLPGELAK(gl)HAVSEGTK_
HIST3H2BB Ubiquitylation K121 -0.997 0.088 _AVTK(gl)YTSSK_
HIST3H2BB Ubiquitylation K6 -0.872 -0.694 _PDPSK(gl)SAPAPK_
HIST3H2BB Ubiquitylation K86 0.468 _LAHYNK(gl)R_

Background Information for HIST3H2BB:


Pubmed-HIST3H2BB »
Uniprot-HIST3H2BB »
Biogrid-HIST3H2BB »
ProteomicsDB-HIST3H2BB »

Tumorportal-HIST3H2BB »
COSMIC-HIST3H2BB »
GenomeRNAi-HIST3H2BB »
Genecards-HIST3H2BB


Protein-protein Interactions for HIST3H2BB
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in HIST3H2BB
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Histone_core_D IPR007125 0.12
Category members Histone-fold IPR009072 0.01
Category members Histone_H2B IPR000558 0
Category members CBFA_NFYB_domain IPR003958 0


Protein complexes (CORUM database) featuring HIST3H2BB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1223 H2AX complex, isolated from cells without IR exposure Database 8.51
Category members Corum 1227 H2AX complex II Database 7.93
Category members Corum 1226 H2AX complex I Database 1.58


Categories featuring HIST3H2BB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members Pathway Pathway_351 REACTOME_RNA_POL_I_TRANSCRIPTION 0 8.31
Category members Pathway Pathway_350 REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION 0 7.97
Category members Pathway Pathway_884 REACTOME_MEIOTIC_SYNAPSIS 0 7.46
Category members Pathway Pathway_319 REACTOME_CHROMOSOME_MAINTENANCE 0 7.37
Category members Pathway Pathway_875 REACTOME_MEIOSIS 0 6.39
Category members Pathway Pathway_1281 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE 0 4.19
Category members Pathway Pathway_1312 REACTOME_PACKAGING_OF_TELOMERE_ENDS 0 4.09
Category members GO Category GO:0006334 nucleosome assembly Database 3.77
Category members Pathway Pathway_328 REACTOME_TELOMERE_MAINTENANCE 0 3.74
Category members Pathway Pathway_874 REACTOME_MEIOTIC_RECOMBINATION 0 3.7
Category members Pathway Pathway_1139 REACTOME_RNA_POL_I_PROMOTER_OPENING 0 3.56
Category members GO Category GO:0000786 nucleosome Database 2.41
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_889 KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS 0 0.9
Category members Pathway Pathway_920 REACTOME_AMYLOIDS 0 0.68
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18


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