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Query: HIST2H3A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HIST2H3A 0 1.598
HIST2H3A 0 1.598 -0.118 0.659
HIST2H3A 0 1.598 -0.645

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HIST2H3A Ubiquitylation K19 -0.191 1.088 _K(gl)QLATK(gl)AAR_
HIST2H3A Ubiquitylation K80 -0.762 0.886 _EIAQDFK(gl)TDLR_
HIST2H3A Ubiquitylation K57 0.195 0.849 _YQK(gl)STELLIR_
HIST2H3A Ubiquitylation K24 0.496 0.281 _K(gl)QLATK(gl)AAR_
HIST2H3A Ubiquitylation K123 -1.638 0.066 _VTIMPK(gl)DIQLAR_
HIST2H3A Ubiquitylation K37 -1.564 _SAPSTGGVK(gl)KPHR_
HIST2H3A Ubiquitylation K38 -1.512 _SAPSTGGVK(gl)KPHR_
HIST2H3A Ubiquitylation K37 -1.968 _SAPATGGVK(gl)KPHR_
HIST2H3A Ubiquitylation K38 -0.934 _SAPATGGVKK(gl)PHR_

Background Information for HIST2H3A:


Pubmed-HIST2H3A »
Uniprot-HIST2H3A »
Biogrid-HIST2H3A »
ProteomicsDB-HIST2H3A »

Tumorportal-HIST2H3A »
COSMIC-HIST2H3A »
GenomeRNAi-HIST2H3A »
Genecards-HIST2H3A


Protein-protein Interactions for HIST2H3A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PHAX Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP72 Cat. description Hein, Mann, Cell 2015


Protein Domains in HIST2H3A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Histone_core_D IPR007125 0.12
Category members Histone-fold IPR009072 0.01
Category members Histone_H3/CENP-A IPR000164 0


Protein complexes (CORUM database) featuring HIST2H3A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HIST2H3A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members Pathway Pathway_351 REACTOME_RNA_POL_I_TRANSCRIPTION 0 8.31
Category members Pathway Pathway_350 REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION 0 7.97
Category members Pathway Pathway_875 REACTOME_MEIOSIS 0 6.39
Category members GO Category GO:0006334 nucleosome assembly Database 3.77
Category members Pathway Pathway_874 REACTOME_MEIOTIC_RECOMBINATION 0 3.7
Category members Pathway Pathway_1139 REACTOME_RNA_POL_I_PROMOTER_OPENING 0 3.56
Category members GO Category GO:0000786 nucleosome Database 2.41
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_889 KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS 0 0.9
Category members Pathway Pathway_920 REACTOME_AMYLOIDS 0 0.68
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members Pathway Pathway_385 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 0 0.07


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