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Query: HELB

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HELB 0 0.476 1.030 -0.690

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HELB Phosphorylation S1048 0.877 _RTCGVNDDES(ph)PSK_
HELB Phosphorylation S1058 0.701 _IFMVGES(ph)PQVSSR_
HELB Phosphorylation S967 -0.401 -0.259 _LSSSGAPPADFPS(ph)PR_

Background Information for HELB:


Pubmed-HELB »
Uniprot-HELB »
Biogrid-HELB »
ProteomicsDB-HELB »

Tumorportal-HELB »
COSMIC-HELB »
GenomeRNAi-HELB »
Genecards-HELB


Protein-protein Interactions for HELB
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SEPT9 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCNA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POLR2E Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HELB
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83


Protein complexes (CORUM database) featuring HELB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HELB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0004003 ATP-dependent DNA helicase activity Database 4.66
Category members GO Category GO:0006260 DNA replication Database 3.34
Category members GO Category GO:0006261 DNA-dependent DNA replication Database 0.48
Category members GO Category GO:0043141 ATP-dependent 5'-3' DNA helicase activity Database 0.25
Category members GO Category GO:0005658 alpha DNA polymerase:primase complex Database 0
Category members GO Category GO:0006269 DNA replication, synthesis of RNA primer Database 0
Category members GO Category GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity Database 0


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