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Query: HADHB

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HADHB 0 -0.514 1.190 -0.950 0.120 -0.958 -0.345 0.537 0.132

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for HADHB:


Pubmed-HADHB »
Uniprot-HADHB »
Biogrid-HADHB »
ProteomicsDB-HADHB »

Tumorportal-HADHB »
COSMIC-HADHB »
GenomeRNAi-HADHB »
Genecards-HADHB


Protein-protein Interactions for HADHB
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDH1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KPNB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MGP Cat. description Hein, Mann, Cell 2015
Category members IP bait MYC Cat. description Hein, Mann, Cell 2015
Category members IP bait NAF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NES Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKAR2A Cat. description Hein, Mann, Cell 2015
Category members IP bait SMN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TNPO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CD44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RELL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YBEY Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HADHB
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Thiolase-like IPR016039 0.26
Category members Thiolase IPR002155 0
Category members Ketoacyl_synth_N IPR014030 0
Category members Thiolase_N IPR020616 0
Category members Thiolase_C IPR020617 0


Protein complexes (CORUM database) featuring HADHB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HADHB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0051287 NAD binding Database 1.6
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0042645 mitochondrial nucleoid Database 0.61
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members GO Category GO:0005741 mitochondrial outer membrane Database 0.46
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups Database 0.33
Category members Pathway Pathway_133 KEGG_FATTY_ACID_METABOLISM 0 0.31
Category members Pathway Pathway_1 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM 0 0.23
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members Pathway Pathway_145 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION 0 0.05
Category members Pathway Pathway_19 KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION 0 0.04
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_161 REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Disease phenotype Mitochondrial_trifunctional_protein_deficiency Mitochondrial trifunctional protein deficiency Database 0
Category members Disease phenotype TRIFUNCTIONAL_PROTEIN_DEFICIENCY TRIFUNCTIONAL PROTEIN DEFICIENCY Database 0
Category members GO Category GO:0000062 fatty-acyl-CoA binding Database 0
Category members GO Category GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity Database 0
Category members GO Category GO:0003988 acetyl-CoA C-acyltransferase activity Database 0
Category members GO Category GO:0004300 enoyl-CoA hydratase activity Database 0
Category members GO Category GO:0005740 mitochondrial envelope Database 0
Category members GO Category GO:0006635 fatty acid beta-oxidation Database 0
Category members GO Category GO:0006644 phospholipid metabolic process Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0016507 mitochondrial fatty acid beta-oxidation multienzyme complex Database 0
Category members GO Category GO:0016508 long-chain-enoyl-CoA hydratase activity Database 0
Category members GO Category GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity Database 0
Category members GO Category GO:0035965 cardiolipin acyl-chain remodeling Database 0
Category members GO Category GO:0044255 cellular lipid metabolic process Database 0
Category members GO Category GO:0046474 glycerophospholipid biosynthetic process Database 0


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