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Query: HACL1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HACL1 0 -1.594 0.570 -0.190 0.582 -0.243

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HACL1 Ubiquitylation K234 -0.466 _GAAYAHAEESIK(gl)K_
HACL1 Ubiquitylation K365 -0.881 _SNEAASK(gl)ELASKK_
HACL1 Ubiquitylation K540 -1.467 _GYFVQTPEELQK(gl)SLR_

Background Information for HACL1:


Pubmed-HACL1 »
Uniprot-HACL1 »
Biogrid-HACL1 »
ProteomicsDB-HACL1 »

Tumorportal-HACL1 »
COSMIC-HACL1 »
GenomeRNAi-HACL1 »
Genecards-HACL1


Protein-protein Interactions for HACL1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HACL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ODF2L Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HACL1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members THDP-binding IPR029061 0.04
Category members TPP_enzyme-bd_C IPR011766 0
Category members Thiamin_PyroP_enz_cen_dom IPR012000 0
Category members Thiamin_PyroP_enz_TPP-bd_dom IPR012001 0
Category members DHS-like_NAD/FAD-binding_dom IPR029035 0


Protein complexes (CORUM database) featuring HACL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HACL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0005782 peroxisomal matrix Database 0.23
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0016830 carbon-carbon lyase activity Database 0.08
Category members GO Category GO:0048037 cofactor binding Database 0.08
Category members Pathway Pathway_26 REACTOME_PEROXISOMAL_LIPID_METABOLISM 0 0.04
Category members Pathway Pathway_25 KEGG_PEROXISOME 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members GO Category GO:0000287 magnesium ion binding Database 0
Category members GO Category GO:0001561 fatty acid alpha-oxidation Database 0
Category members GO Category GO:0005102 receptor binding Database 0
Category members GO Category GO:0005777 peroxisome Database 0
Category members GO Category GO:0006629 lipid metabolic process Database 0
Category members GO Category GO:0016829 lyase activity Database 0
Category members GO Category GO:0030976 thiamine pyrophosphate binding Database 0
Category members GO Category GO:0044255 cellular lipid metabolic process Database 0
Category members GO Category GO:0051259 protein oligomerization Database 0


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