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Query: GYS1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GYS1 0 -1.206 1.000 -0.130 -0.800 0.561 0.380

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GYS1 Phosphorylation S727 0.148 -0.041 _RNSVDTATSSSLSTPSEPLS(ph)PTSSLGEERN_
GYS1 Ubiquitylation K381 -0.746 -0.708 _TNNFNVETLK(gl)GQAVR_
GYS1 Ubiquitylation K88 -1.746 -1.039 _TQVELLEAPTPALK(gl)R_

Background Information for GYS1:


Pubmed-GYS1 »
Uniprot-GYS1 »
Biogrid-GYS1 »
ProteomicsDB-GYS1 »

Tumorportal-GYS1 »
COSMIC-GYS1 »
GenomeRNAi-GYS1 »
Genecards-GYS1


Protein-protein Interactions for GYS1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GBE1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GYG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP1CA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP1CC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP1R3C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRKAB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STBD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GYS1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Glycogen_synth IPR008631 0.32
Category members Glyco_trans_1 IPR001296 0


Protein complexes (CORUM database) featuring GYS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GYS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_35 REACTOME_GLUCOSE_METABOLISM 0 1.79
Category members Pathway Pathway_455 PID_INSULIN_GLUCOSE_PATHWAY 0 1.7
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0004373 glycogen (starch) synthase activity Database 0.32
Category members Pathway Pathway_34 REACTOME_METABOLISM_OF_CARBOHYDRATES 0 0.31
Category members GO Category GO:0006006 glucose metabolic process Database 0.28
Category members Pathway Pathway_44 KEGG_INSULIN_SIGNALING_PATHWAY 0 0.21
Category members GO Category GO:0016234 inclusion body Database 0.14
Category members GO Category GO:0009058 biosynthetic process Database 0.11
Category members GO Category GO:0005977 glycogen metabolic process Database 0.08
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members GO Category GO:0005978 glycogen biosynthetic process Database 0.04
Category members Pathway Pathway_60 KEGG_STARCH_AND_SUCROSE_METABOLISM 0 0
Category members GO Category GO:0005536 glucose binding Database 0
Category members GO Category GO:0007507 heart development Database 0


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