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Query: GTF3C4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GTF3C4 0 4.697 0.860 0.000 0.093 0.071 0.710 0.425 0.393

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GTF3C4 Ubiquitylation K137 0.416 1.107 _FAASK(gl)DPTVSQTFMLDR_
GTF3C4 Ubiquitylation K123 1.287 0.177 _VGSK(gl)TEVAECK_
GTF3C4 Phosphorylation S611 0.441 0.170 _ILLVDS(ph)PGMGNADDEQQEEGTSSK_
GTF3C4 Ubiquitylation K225 -0.330 -0.022 _LSK(gl)NEAPEGNLGDFAEFQR_
GTF3C4 Ubiquitylation K119 -0.474 -0.928 _TSVPAPLNSCLLK(gl)VGSK_
GTF3C4 Ubiquitylation K633 0.210 -1.180 _QVVK(gl)QGLQER_
GTF3C4 Ubiquitylation K736 0.213 _VLIGHISK(gl)K_
GTF3C4 Ubiquitylation K737 0.213 _VLIGHISK(gl)K_

Background Information for GTF3C4:


Pubmed-GTF3C4 »
Uniprot-GTF3C4 »
Biogrid-GTF3C4 »
ProteomicsDB-GTF3C4 »

Tumorportal-GTF3C4 »
COSMIC-GTF3C4 »
GenomeRNAi-GTF3C4 »
Genecards-GTF3C4


Protein-protein Interactions for GTF3C4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAG2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX8 Cat. description Hein, Mann, Cell 2015
Category members IP bait GTF3C2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GTF3C3 Cat. description Hein, Mann, Cell 2015
Category members IP bait GTF3C4 Cat. description Hein, Mann, Cell 2015
Category members IP bait NOP56 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait ZNF785 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GTF3C4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39


Protein complexes (CORUM database) featuring GTF3C4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1106 TFIIIC containing-TOP1-SUB1 complex Database 0.72
Category members Corum 1114 5S-DNA-TFIIIA-TFIIIC2-TFIIIB subcomplex Database 0.25
Category members Corum 1101 TFIIIC containing complex TFIIIC2 Database 0.23
Category members Corum 1105 TFIIIC containing complex Database 0.23
Category members Corum 1113 5S-DNA-TFIIIA-TFIIIC2 subcomplex Database 0.08


Categories featuring GTF3C4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members Pathway Pathway_350 REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION 0 7.97
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0016573 histone acetylation Database 1.24
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0043085 positive regulation of catalytic activity Database 0.78
Category members GO Category GO:0004402 histone acetyltransferase activity Database 0.56
Category members Pathway Pathway_355 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER 0 0.37
Category members Pathway Pathway_357 REACTOME_RNA_POL_III_TRANSCRIPTION 0 0.29
Category members GO Category GO:0006383 transcription from RNA polymerase III promoter Database 0.18
Category members GO Category GO:0008047 enzyme activator activity Database 0.15
Category members GO Category GO:0000127 transcription factor TFIIIC complex Database 0.08
Category members GO Category GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter Database 0.08
Category members GO Category GO:0042797 tRNA transcription from RNA polymerase III promoter Database 0.08
Category members GO Category GO:0006384 transcription initiation from RNA polymerase III promoter Database 0.01


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