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Query: GTF3C3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GTF3C3 0 0.753 1.180 -0.630 -0.946 0.315 0.638 0.498 0.490

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GTF3C3 Phosphorylation S43 0.108 0.230 _LS(ph)AEENPDDSEVPSSSGINSTK_
GTF3C3 Ubiquitylation K245 -0.753 -0.309 _ALK(gl)YEPTNVR_
GTF3C3 Ubiquitylation K268 -0.270 _SSLYEQMGDHK(gl)MAMDGYR_

Background Information for GTF3C3:


Pubmed-GTF3C3 »
Uniprot-GTF3C3 »
Biogrid-GTF3C3 »
ProteomicsDB-GTF3C3 »

Tumorportal-GTF3C3 »
COSMIC-GTF3C3 »
GenomeRNAi-GTF3C3 »
Genecards-GTF3C3


Protein-protein Interactions for GTF3C3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait GTF3C2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GTF3C3 Cat. description Hein, Mann, Cell 2015
Category members IP bait GTF3C4 Cat. description Hein, Mann, Cell 2015
Category members IP bait MRPL50 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCDH1 Cat. description Hein, Mann, Cell 2015
Category members IP bait UBR5 Cat. description Hein, Mann, Cell 2015
Category members IP bait BIN3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CASQ2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF764 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF785 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GTF3C3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TPR_1 IPR001440 1.39
Category members TPR-contain_dom IPR013026 0.97
Category members TPR_repeat IPR019734 0.93
Category members TPR_2 IPR013105 0.45


Protein complexes (CORUM database) featuring GTF3C3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1106 TFIIIC containing-TOP1-SUB1 complex Database 0.72
Category members Corum 1114 5S-DNA-TFIIIA-TFIIIC2-TFIIIB subcomplex Database 0.25
Category members Corum 1101 TFIIIC containing complex TFIIIC2 Database 0.23
Category members Corum 1105 TFIIIC containing complex Database 0.23
Category members Corum 1113 5S-DNA-TFIIIA-TFIIIC2 subcomplex Database 0.08


Categories featuring GTF3C3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members Pathway Pathway_350 REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION 0 7.97
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_355 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER 0 0.37
Category members Pathway Pathway_357 REACTOME_RNA_POL_III_TRANSCRIPTION 0 0.29
Category members GO Category GO:0006383 transcription from RNA polymerase III promoter Database 0.18
Category members GO Category GO:0000127 transcription factor TFIIIC complex Database 0.08
Category members GO Category GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter Database 0.08
Category members GO Category GO:0042797 tRNA transcription from RNA polymerase III promoter Database 0.08


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